Perfusion with Alternating Tangential Flow (ATF) Device Cultivates Higher Cell Culture Densities while Retaining High Cell Viabilities
BIOLOGICS MANUFACTURING ASIA 2020UPSTREAM PROCESSING
Tuesday, July 7
2:20 pm - 2:45 pm
MSAT Upstream part leader,
Case study on how Samsung Biologics enabled reduced production time using N-1 (3,000L) Perfusion with Alternating Tangential Flow (ATF) Device.
Achieving higher cell culture densities (up to 10-fold) whilst retaining high cell viabilities (>98%) at the seed stage (N-1) to enable inoculation of the production bioreactors (15,000L) at higher cell densities and achieve peak cell densities within shorter culture durations.