Postdoctoral fellow
Yale School of Medicine
Research on cellular signaling in sperm capacitation and fertilization
Link:
http://www.jeanjuchunglab.org/opportunities
Postdoctoral Position studying DNA repair and chromosome biology during meiosis
The University of Texas MD Anderson Cancer Center
Our lab studies the underlying mechanisms that ensure accurate pairing and segregation of homologous chromosomes during meiosis in mammals. We focus on systemic errors that arise in human meiosis such as mis-segregation due to age in spermatocytes and oocytes. Our work takes advantage of genetics in the mouse to determine the
fundamental biology of meiotic chromosome segregation.
We have developed assays to provide high-resolution mapping of
recombination outcomes on all four chromatids (Cole F, Baudat F et al
Nature Genetics 2014) to determine the molecular nature of individual
events and to biochemically and genetically delineate contributions from DNA repair pathways (Zelazowski M et al Cell 2017). We have developed methods to purify spermatocytes at specific stages to investigate the timing of recombination and chromosome organization during meiotic prophase (Patel L, Kang R et al Nature Structural and Molecular Biology, 2019). Finally, the lab couples these molecular approaches with advanced microscopy (Cole F et al Nature Cell Biology 2012) to provide a holistic view of recombination during mouse and human meiosis.
Link:
https://www.mdanderson.org/research/departments-labs-institutes/labs/colelaboratory. html
Postdoctoral Fellow
Washington University School of Medicine
The Santi lab studies the molecular mechanisms involved in sperm capacitation, in both mice and human. We are specially interested in how changes in sperm electrical activity and ion channel function affect the sperm fertility capacity. We also are interested in developing new methods to assess the ability of sperm to capacitate and fertilize an oocyte, and in developing novel contraceptive drugs
Candidate qualifications:
• A recent PhD or MD/PhD degree (or candidate) in Biochemistry, Biophysics, Molecular, Cell and Developmental Biology or Reproductive Biology
• Background in protein biochemistry, electrophysiology, calcium imaging, use of membrane potential or pH- sensitive dyes, flow cytometry and/or experience with mice/human gametes and embryos.
To apply, please send a single PDF file to santic@wustl.edu which should include
(1) a statement of research interests and career goals, (2) curriculum vitae, and (3) a list of three references.
Post-doctoral Researcher in Germ cell and RNA Biology
Rutgers University
A postdoctoral position is available in the laboratory of Dr. Elizabeth Snyder. The ideal candidate will have strong communication skills, a publication record consistent with career level, and an interest in understanding the influence of RNA biology on germ cell development in mammals. Experience in molecular biology and proficiency in bioinformatic analysis of RNA-sequencing data, plus proficiency in oral and written English are required. Preferred is a background in RNA biology and/or germ cell biology, and experience with transgenic mouse models. Salary will be commensurate with experience and follow NIH and Rutgers guidelines. The position is based in the Snyder laboratory, an interdisciplinary and energetic research group housed on the Cook campus of Rutgers University in New Brunswick, NJ. In addition to advanced scientific training; post-doctoral researchers in the Snyder laboratory receive training in bioinformatics analysis techniques, imaging modalities, grantsmanship, and scientific communication. As a postdoctoral associate, the candidate would have abundant opportunities to interact with members of the vibrant reproductive biology community within Rutgers University and the Department of Animal Sciences. The campus is also in close proximity to the cultural and scientific offerings of both NYC and Philadelphia.
For more information on the Snyder Laboratory, please visit: https://animalsciences.rutgers.edu/faculty/snyder/
Link:
https://jobs.rutgers.edu/postings/127582
Postdoctoral Research Associate
University of Illinois at Urbana Champaign
Postdoctoral position open to work on the role of transcription factors in the regulation of spermatogenesis. Current focus is on the role of TDP-43 and RNA Pol II pausing on gene expression in male germ cells in mice. Conditional knockout of TDP-43 as well as NELF led to male infertility (poster by Zomer et al. in this meeting). The incoming postdoc will utilize CLIP, RNA-seq, and reporter assays to investigate the functional roles of TDP-43 and NELF in male germ cells and Sertoli cells. The position is funded by NIH R01; funding available for 2 years with the possibility of extension. Please send CV and the names of 3 references to preddi@illinois.edu
Link:
https://vetmed.illinois.edu/reddi-lab/
