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Postdoc or graduate student position to study circadian rhythms in pregnancy
Michigan State University
The Hoffmann lab, studying neuroendocrinology and circadian rhythms at Michigan State University is recruiting a motivated, and skilled postdoc (Research Associate) or graduate student interested in the neuroendocrine control of pregnancy.
Research in the Hoffmann lab (https://www.canr.msu.edu/hoffmann/) is focused on understanding the role of circadian rhythms in women’s health, pregnancy and labor. Using combined in vivo and in vitro approaches, we are increasing our understanding of the contribution of the molecular clock and circadian rhythms in reproductive tissues, the brain and their role in pregnancy and labor onset.
The lab uses a wide range of transgenic mouse models, behavioral studies, hormone analysis, fresh tissue recordings, cell culture, histology, IHC, as well as molecular and genomic analysis tools.
Specific Position Duties
• Perform and develop experiments using advanced biomedical research techniques
• Writing scientific publications
• Present results at national and international scientific meetings
• Get trained in writing grant applications to major funding agencies
• Supervising students
Qualifications
Minimal requirements (these requirements are adjusted to the applicant postdoc/graduate student application)
• For postdoc position: PhD in relevant scientific area (Neuroscience, Endocrinology, Biochemistry Molecular and Cellular Biology or other)
• Ability to work independently as well as in a group
• Excellent communication and organizational skills
• A strong work ethic and a commitment to significantly contribute to the advancement of the project
• Excellent skills in scientific writing
Proficiency in one or more of these fields is desirable, but not required: molecular biology (PCR, qPCR, RNA, cloning), optogenetics, stereotaxic injections, microscopy, mice (surgeries, behavioral studies), cell culture, circadian rhythms.
For more information about this position, please contact Dr. Hanne Hoffmann: hanne@msu.edu

Link: https://www.canr.msu.edu/hoffmann/
Post-doctoral Researcher in Clinical Physiology and Chronobiology
Oregon Health & Science University
Required Qualifications: PhD and/or MD
Preferred experience, knowledge or qualities:
• Human cardiovascular, sleep, and/or circadian physiology, and advanced statistics
• Managing human subjects IRB protocols, budgets
• Managing research assistants
• Ability to be self-motivated, to prioritize effectively and achieve deadlines
• Ability to work overnight hours and occasional weekends for data collection
The Clinical Physiology and Chronobiology Program (CPCP): The CPCP is located in the Oregon Institute of Occupational Health Sciences at OHSU. The CPCP specializes in clinical research on the effects of sleep and circadian rhythms on physiology and pathophysiology in humans.
Functions/Duties of Position: The successful candidate will work on multiple projects examining the biological basis of physiological and pathophysiological changes across the day and night, including mechanisms underlying the morning peak in adverse cardiovascular events. There will also be a focus on health disparities. The Postdoctoral fellow will serve as a project leader on NIH funded research under the direction of Nicole P. Bowles, PhD and Steven A. Shea, PhD (PIs). Primary duties will include developing scientific ideas, writing grant applications and manuscripts, data collection and management, and supervision of research assistants.
To apply please use OHSU iRecruitment to upload a letter of application, Curriculum Vitae/Resume, contact information for three academic/professional references, and a published paper. For more information contact bowlesn@ohsu.edu or sheast@ohsu.edu.

Link: https://externalcareers-ohsu.icims.com/jobs/7986/postdoctoral-researcher/job?mobile=true&width=1024&height=569&bga=true&needsRedirect=false&jan1offset=-480&jun1offset=-420
2-years post-doctoral fellowship in Cancer Clocks
University of Warwick
This position is associated with a three years CRUK funded Multidisciplinary Award jointly lead by Dr Robert Dallmann (WMS) and Professor David A. Rand (Maths) to determine if the circadian clock in cancer cells holds potential to predict cancer patient survival. The Research Fellow will be based in Biomedical Sciences Division of WMS and work in the new Inter-disciplinary Biomedical Research Building at the Gibbet Hill Campus Site of University of Warwick. However, you will also work in close collaboration with the project team of Mathematicians, Statisticians and Bioinformaticians.

The fellow will play a key role in the gathering, analysis and interpretation of transcriptomic data from time-series collections of in vitro models. We have previously shown the potential of estimating the circadian cock status and phase from the transcriptome of tumour biopsies using mathematical modeling. This inter-disciplinary project will further develop this idea towards an actionable clinical biomarker. During the course of the project we will be taking advantage of publicly available data-sets of circadian time-series of tissue transcriptomes as well as repositories of clinical samples as well as generating further data under well defined experimental conditions in order to explore the possible mechanism of circadian disruption.

Please do get in touch should you be interested. Ideally, we are looking for someone to start in April 2021 for 2 years.
Postdoctoral position to study the cellular mechanisms of sleep functions
Washington University in St. Louis
We are seeking a highly motivated candidate for a postdoc position to study the cellular mechanisms of sleep functions. We use optical biosensors, fluorescence lifetime photometry, 2-photon fluorescence lifetime imaging microscopy, electrophysiology and opto/chemogenetics to image and manipulate neuromodulators and intracellular signals associated with sleep/wake cycle. We combine mechanistic dissection in acute brain slices and functional analyses in behaving mice.
I am committed to mentoring and building a diverse team where we support, enrich, and inspire each other, and help every individual find their self-expression through science.

We are open to highly motivated and genuinely interested candidates from diverse backgrounds, including but not limited to neuroscience, molecular and cell biology, biophysics, systems biology, and engineering. We especially encourage applications from candidates with expertise in animal behavior, circadian/sleep biology, systems neuroscience, and/or quantitative data analysis.

If you are interested in joining us as a postdoc, please email me with a) a cover letter describing your past research and future interests, b) your CV, including a list of publications, and c) the names and contact information of three references.

Link: https://sites.wustl.edu/yaochenlab/
Postdoctoral or Research Scientist position
Uniformed Services University
Chronobiology, light and sleep lab (human lab and field studies)
Bs/Ms position
University of California San Diego
The Desplats Lab has an opening for a student of the UCSD contiguous Bs/Ms program. The project will investigate circadian clock alterations in Alzheimer's disease redone models at the level of transcriptional regulation, as part of a major study including multi-omic analysis; circadian interventions and epigenetic studies. Previous hands-on experience in the bench is required (BISP199/volunteer/internship) and good command of basic biochemistry and/or molecular biology techniques. We are a vibrant and highly collaborative group of researchers working in translational science.
Link: https://medschool.ucsd.edu/som/neurosciences/research/labs/desplats/Pages/default.aspx
Postdoc - WashU Neurology Dept - circadian and limbic systems
Washington University School of Medicine
We are looking for a talented and creative neuroscientist to join us in exploring how the circadian system influences limbic system functions during aging and Alzheimer's disease progression. We have several funded projects that use a combination of approaches including in vivo optogenetics, electrophysiology, actigraphy, behavior assays, protein and mRNA quantification and localization. Interested postdoc applicants, please email us your CV with references and a cover letter describing your past projects and career goals. Looking forward to hearing from you!
Link: https://www.kresslab.org/
Post-Doctoral Research Opportunity: Circadian Rhythms in Neuronal Models of Bipolar Disorder
UC San Diego Department of Psychiatry/ VA San Diego Healthcare
The laboratory of Michael McCarthy MD, PhD seeks an energetic and motivated post-doctoral researcher. The overall goals of the project are to develop novel cellular models of bipolar disorder using iPSC-derived neurons and use this platform to identify and characterize differences in circadian rhythms that distinguish patients with bipolar disorder from controls and inform treatments with mood stabilizer medications. Leveraging clinical treatment trials and genetic family studies, the project will make use of well-described cohorts of bipolar disorder patients and genetically related healthy subjects. We use viral vectors to express circadian reporter genes in neurons and measure rhythms in live cultures and single cells. We characterize the circadian clock further using genomic, physiological and structural approaches to characterize neurons. The project will be an excellent opportunity for a basic science researcher to pursue novel applications of cutting-edge biological research techniques and explore an area with extraordinary potential for clinical translation. The research group is funded by the Department of Veterans Affairs and housed at the VA Medical Center. An academic appointment will be made through the University of California, San Diego Department of Psychiatry, one of the top translational neuroscience research programs in the country, and core member of the UCSD Center for Circadian Biology, an internationally recognized research center, providing additional resources and a rich training environment for fellows.

Requirements: PhD degree in a relevant biological science, >3 years of laboratory experience, Excellent communication and organization skills. Previous experience in stem cell biology is highly desirable.

Interested applicants should email Dr. McCarthy and includes the following information: CV, cover letter, and contact information for at least three references willing to write a letter of support: mmccarthy@health.ucsd.edu
Link: https://profiles.ucsd.edu/michael.mccarthy#toc-id1
PostDoc or Research Associate
University of Guelph
Circadian-Cardiovascular Research. We're looking for a Postdoc or Research Associate with a strong background in circadian biology. Applicants will learn state-of-the-art cardiovascular molecular biology, and physiology. Projects are pre-clinical (rodent) Circadian Medicine therapies to benefit the treatment of heart disease - our #1 leading cause of death. Current projects investigate ChronoTherapy, ChronoExercise, and ChronoNutrition.
Link: https://ovc.uoguelph.ca/biomedical-sciences/people/faculty/Tami-Martino
Post doc or Research Scientist and Graduate students
University of Saskatchewan
This is one year (or more) funded post doc or research associate position and funded positions for graduate students in Saskatoon, one of the fastest growing cities in Canada. With larger amount of sunny days compared to other North America cities and with close proximity to beautiful National parks including the Rockies, Saskatoon is ideal place to raise a family. This job and training opportunities are for persons with interest in precision health and circadian clock. Our lab is very diverse studying the role of circadian clock disruption into autoimmunity and cancer. We study from biological questions regarding signalling and stem cells, to microbial host interactions, to nutrition and epigenetic signatures, to chronotherapy and biosensor development for human monitoring. We look for people with experience in circadian clock biology ready to function in a truly trans disciplinary environment. Bioinformatics and microbiology expertise are additional assets.
Link: None
PostDoc positions in Circadian Bioinformatics (Cancer & Neurodegeneration)
University of Pennsylvania
We are looking to recruit 1 or 2 postdoctoral fellows.

The lab focuses on understanding the influence of sleep and circadian rhythms on physiology and disease using techniques from engineering, bioinformatics, and machine learning.

Ongoing, NIH funded projects are concentrated on understanding circadian pathways in cancer and neurodegeneration. Collaborative projects combine computational analysis with experiments to identify new diagnostic tools and/or rational targets for chronotherapy.

We are looking for curious, self-driven folks with a strong quantitative/computational background. A background in bioinformatics or biomedical data analysis is preferred but not essential.

If interested, please email me with a cover letter, CV, and contact info for three references.
Link: https://www.med.upenn.edu/apps/faculty/index.php/g275/p8198976
PhD in circadian neuroimmunology
Queen's University
Our lab is seeking applications from outstanding candidates interested in pursuing PhD studies in neuroimmunology and pain physiology. We use animal models of postsurgical pain, chronic neuropathy, spinal cord injury, multiple sclerosis, and Lyme disease, and also studies changes in people living with chronic pain. Current projects include:
• Neuro-immune control of dendritic cell activation in post-operative pain
• Peripheral and central neuroinflammation in chronic Lyme disease pain
• Identifying biomarkers of chronic low back pain using RNA-Seq

Projects in our lab seek to dissect mechanisms underlying interactions between the nervous and immune systems, with a focus on pain. All PhD projects will span clinical (human) and preclinical (mouse) studies, and will use a wide spectrum of approaches, including animal behavior, micro-surgery, molecular biology (flow cytometry, RNA/protein work, immunofluorescence, cell culture), and genetically-modified mouse models. Self-motivated individuals with background (BSc, MSc) in a relevant field (neurosciences, immunology, circadian biology, epidemiology) are encouraged to apply. Candidates must be creative, capable of working independently and in groups, and will be expected to analyze data and write manuscripts.

Interested candidates should send a brief cover letter, CV, transcripts, and names/contact details of at least one reference to Dr. Nader Ghasemlou at nader.ghasemlou@queensu.ca.
Link: https://www.ghasemloulab.ca
Post-doctoral fellowship in sleep
University of Pennsylvania
We have an NIH-funded postdoctoral position starting July 2021. The lab studies mechanisms of sleep, with a particular emphasis on sleep during sickness. Our chief model organism for these studies is the nematode C. elegans. This project would involve genetic discovery approaches, transgenesis, molecular methods, microscopy, and behavioral analysis.

We are looking for curious, self-driven scientists with a strong foundation in wet-bench science. A background in molecular genetics is is preferred but not essential. If interested, please email me with a cover letter, CV, and contact info for three references.
Link: https://www.med.upenn.edu/raizen-lab/
Post-Doctoral Fellow
Rensselaer Polytechnic Institute
The Hurley lab at Rensselaer Polytechnic Institute (https://homepages.rpi.edu/~hurlej2/) is seeking post-doctoral fellows. These NIH, NSF, DOE, and privately funded positions have the flexibility to focus on one of several topics of ongoing research in the lab, all centered around the investigation of the interface between the mechanisms that allow the TTFL to impart regulation on biological systems and the effect the disruption of this regulation can have on the health of an organism. Our research utilizes several models, including primary cells, mice, and the fungus Neurospora crassa. Experimental approaches include protein biochemistry/biophysics, cell and molecular biology, genetics, immunology, Alzheimer’s Disease, and systems biology.

Successful applicants should have a Ph.D. in a related field and a demonstrated track record of productivity. Experience in circadian biology is a plus but is not a requirement and projects can and will be tailored to the candidates interests and qualifications. A successful candidate will be expected to work both independently and as part of an interactive team, have a strong work ethic, and take a leadership role in the lab. The Hurley lab, RPI, and CBIS together offer a unique opportunity to work at the cross-roads of basic and applied sciences, granting the successful applicant a remarkable training experience.

Applicants should send a CV, a cover letter, and the name, address, email and phone numbers of three references to Dr. Hurley via email: Hurlej2@rpi.edu

Jennifer Hurley, Richard Baruch, M.D. Assistant Professor in the Dept. of Biological Sciences, Rensselaer Polytechnic Institute, Center for Biotechnology and Interdisciplinary Sciences, Troy, NY 12018. Rensselaer Polytechnic Institute is an Equal Opportunity and Affirmative Action Employer.
Link: https://homepages.rpi.edu/~hurlej2/
Postdoctoral Positions in the Physiology of Non-Visual Photoreception
Cincinnati Children's Hospital
A full time Postdoctoral position is available in the laboratory of Prof. Richard Lang at the Visual Systems Group (Pediatric Ophthalmology) and Center for Chronobiology, Cincinnati Children’s Hospital, United States. We are seeking highly motivated applicants to investigate light receptors, circadian biology, metabolic regulation, and nervous system development. The ideal candidate is expected to work both independently and as part of an interactive team. Full-time positions are available for up to 5 years pending satisfactory performance.

Starting date: As soon as possible.

The Lang lab is currently working to understand how the atypical opsins OPN3 (encephalopsin), OPN4 (melanopsin) and OPN5 (neuropsin) regulate light-dependent development and homeostasis. In recent work, we have shown that both melanopsin (Rao et al., Nature, 2013) and neuropsin (Nguyen et al., Nature Cell Biology, 2019) provide timing cues for vascular development in the eye. We have also shown that OPN3 in adipocytes (Nayak et al., Cell Reports, 2020) and OPN5 in hypothalamic neurons (Zhang et al., 2020) each regulate body temperature using distinct light response pathways.

This emerging area of investigation promises extremely interesting findings

Qualifications: The ideal candidates will have a PhD in genetics, molecular, cell, or developmental biology (or similar). A thorough theoretical and practical grounding in molecular and cell biology is a prerequisite, and knowledge within the fields of chronobiology and photoreceptors is an advantage. The Lang lab primarily uses the mouse as a model system, and we make heavy use of genetic methods. Thus, experience with this system is also an advantage. The applicants should be proficient in written and spoken English, have good computer skills and understand the basics of quantitative analysis.

To apply for these positions, please contact Richard Lang at richard.lang@cchmc.org
Link: https://www.cincinnatichildrens.org/bio/l/richard-lang
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