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Jobs Posted on the Whova Community Board of Emerging Roles of the Nucleolus

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Postdoc Position in mTOR Signaling in Cancer at Rutgers University
Rutgers University
Postdoctoral opportunities are available to study mTOR signaling in epigenetic regulation and chromatin remodeling during tumorigenesis and cancer therapies. Rutgers University is conveniently located in the New York City metropolitan area. It offers state-of-the-art facilities, and interactive and stimulating scientific environment. For more information, please see our sample publications: Cancer Research. 2021, DOI: 10.1158/0008-5472.CAN-21-0206; Cell Reports 2021, 34: 108830; Nature Comm 2021, 12:2259; Molecular Cell 70:502; Cancer Cell 26:754; Nature 442: 1058; EMBO J 28: 2220 or visit: https://www.cinj.org/zhenglab
We are seeking highly motivated individuals with a recent PhD degree in molecular cellular biology, cancer biology, pharmacology or other related biological sciences. Individuals with experience with genetically engineered mouse models are especially encouraged.

Interested applicants should send a recent CV and names of three references to: Dr. Steven Zheng, University Professor and Chief, Division of Cancer Pharmacology, Rutgers University. Email: zhengst@cinj.rutgers.edu

Link: https://www.cinj.org/zhenglab
Postdoc position in 5'-cap hypermethylation in cancers and viruses
University of MInnesota
Postdoc position in 5'-cap hypermethylation in cancers and viruses
Assistant Investigator
Stowers Institute for Medical Research
The Stowers Institute for Medical Research invites innovative early career scientists in the Life Sciences to submit applications for an Assistant Investigator position in 2022.
Research programs of interest include, but are not limited to biochemistry, biophysics, genetics, neuroscience, cell biology, genomics, epigenetics, evolution, quantitative biology, and synthetic biology. Our interests run the gamut of experimental organisms and approaches.
The successful candidate is expected to develop a groundbreaking, innovative, and independent research program, and will benefit from and complement the Institute’s existing strengths in genetics, developmental/regenerative biology, evolution, biochemistry, and neuroscience. The candidate may also take advantage of exceptional core facilities and technology centers staffed by over 100 scientists, as well as multiple opportunities to be involved in the Institute’s Graduate School program.
Positions at the Institute are exceptional in that they are fully funded throughout the candidate’s appointment. This includes $600,000 per year for research funding and full salary support, in addition to start-up funds and ongoing needs for equipment. The initial appointment is for 7 years and is then subject to renewal every 6 to 7 years. In total, the package for an Assistant Investigator position is more than $4.2 million over the first term and increases significantly after promotion.
Candidates must have a PhD or equivalent degree and postdoctoral experience demonstrating innovation and excellence in their field. Candidates will be expected to possess a long-term vision of their scientific interests and to actively contribute to the Institute’s mission and collegiality.
The deadline for application submission is November 1, 2021.
Questions should be directed to the Search Committee Chair, Kausik Si, PhD, at facultysearch@stowers.org.

Link: https://www.stowers.org/facultysearch
Post-doc – Chromosome Biology of the Human Nucleolus
McStay Lab, Centre for Chromosome Biology (CCB), NUI Galway
Nucleoli, sites of ribosome biogenesis and the largest structures in the human nucleus, form around nucleolar organiser regions (NORs) located on the p-arms of the five acrocentric chromosomes. NORs comprise ribosomal gene (rDNA) arrays coding for the major RNA components of ribosomes. How multiple acrocentric p-arms gather together to form a nucleolus, how NORs partition within nucleoli and how rDNA genomic stability is maintained are important but unanswered questions. The successful candidate will be a key member of a team that will utilise novel chromosome engineering technologies to address these critical questions.
Link: https://www.chromosome.ie/researchers/mcstay/
Postdoc position in nucleolar biophysics during oncogenesis, differentiation, and aging.
Baylor College of Medicine
Positions are available to investigate how the form and function of nucleoli and other biological condensates change during oncogenesis, differentiation, and aging. We are seeking motivated researchers with a desire to work at the interface between cell biology, polymer physics, and physical chemistry. While individuals familiar with nucleolar biology, liquid-liquid phase separation physics, or biophysical chemistry are encouraged to apply, no specific background experience is required. Those interested should send an up-to-date CV and contact information for references to Josh at Joshua.Riback@bcm.edu .

Link: http://www.RibackLab.com
Postdoc position to study rDNA-protein interactions in the context of DNA damage and aging
IGBMC
We're looking for a motivated Postdoc fellow to investigate rDNA-protein interactions in budding yeast by combining proteomics and microfluidic-based imaging. A solid background in molecular and cell biology would be appreciated. If interested, contact Sandrine morlot@igbmc.fr
Postdoctoral Researcher – nucleolus in neurodegeneration
UT Southwestern Medical Center
A postdoctoral training position is available in the laboratory of Dr. Haiyang Yu, a newly appointed assistant professor in the Center for Alzheimer’s & Neurodegenerative Diseases at UT Southwestern Medical Center to study the mechanisms behind neurodegenerative diseases. My laboratory has several exciting projects on liquid-liquid phase separation of nuclear and cytoplasmic RNA bodies. Dr. Yu is also developing a project to determine the dysregulation of nucleolar function during neurodegeneration.

The position will perform specialized research experiments by using model cell lines, iPS-derived neurons, mouse and human brain autopsy samples. Candidates must hold a Ph.D. and/or M.D. degree. Interested candidates must have 1) a strong background in cell biology, molecular biology, RNA biology, or related disciplines, and 2) scientific curiosity and the desire and ability to work independently. Experience with proteomics or nextgen sequencing (i.e. RNA-seq) is a plus.

Please contact me directly. My email is haiyang.yu@utsouthwestern.edu
Postdoctoral Research Associate-Protein Self-Assembly
Stowers Institute for Medical Research
Protein Self-Assembly
The Stowers Institute for Medical Research has an opening for a Postdoctoral Research Associate to join the Halfmann Lab (https://research.stowers.org/halfmannlab/). The lab studies an emerging fundamental feature of biology: nucleation-limited protein phase separation in cells. This research has broad implications for aging, cancer, and neurodegenerative diseases such as Alzheimer’s and ALS. The chosen candidate will develop and execute a project that contributes to the lab’s broader research objectives to understand the mechanisms and biological consequences of protein supersaturation and subsequent self-assembly in living cells, while gaining training in protein biophysics, proteomics, microscopy, cell biology, and science communication.

Successful candidates should have excellent written and verbal communication skills, and the demonstrated ability to lead a project both independently and collaboratively in a team-oriented environment. Attention to detail, tenacity, and the ability to multitask effectively are highly valued.

Minimum requirements include a doctoral degree in biology, biochemistry, cell biology, biophysics, or a related field and at least one first author publication.

To Apply
Submit the requested documents to Dr. Randal Halfmann at rhn@stowers.org cc: careers@stowers.org or to Administration Department, Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 6411
Link: https://www.stowers.org/careers/explore/postdoctoral-research-associate-reqid0001718
Research Specialist-Molecular Simulations
Stowers Institute for Medical Research
The Stowers Institute for Medical Research has an opening for a Research Specialist to join the Halfmann Lab (https://research.stowers.org/halfmannlab). The lab studies a newly discovered but fundamental feature of biology: the storage and release of energy through nucleation-limited protein phase separation in cells. This research has broad implications for aging, cancer, and neurodegenerative diseases such as Alzheimer’s and ALS. The chosen candidate will contribute to the lab’s goals by performing atomistic and/or coarse-grained molecular simulations on both intrinsically disordered proteins (IDPs) and globular proteins.

Knowledge of cutting-edge developments in biophysical models of protein-protein interaction is strongly preferred. Successful candidates should have excellent writing and communication skills, and the demonstrated ability to lead a project both independently and collaboratively in a team-oriented environment. Attention to detail, tenacity, and the ability to multitask effectively are highly valued.

Minimum requirements include a masters or doctorate degree in biology, biochemistry, cell biology, biophysics, or a related field.

To Apply
Submit the requested documents to careers@stowers.org or to Administration Department, Stowers Institute for Medical Research, 1000 E 50th Street, Kansas City, MO 64110.
Link: https://www.stowers.org/careers/explore/research-specialist-0001609
Postdoc position available
Danish Cancer Society
We are looking for a dedicated postdoc to join our team in Copenhagen, Denmark. In our research group, Nucleolar Stress and Disease at the Danish Cancer Society, we investigate how the specialized, repetitive and highly unstable ribosomal RNA genes, is maintained and how their instability promotes tumorigenesis. In spite of the instability of ribosomal DNA (rDNA), its contribution to tumorigenesis is poorly understood.

To address this question, we study the specialised nucleolar DNA damage response (n-DDR) that functions to maintain the integrity of rDNA. We analyse the consequences of nDDR defects and aim to clarify its clinical value.
Link: https://www.cancer.dk/research/dcrc-research/nucleolar-stress-and-disease/
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