Postdoctoral Research Associate in Glycosaminoglycan Biology
University of Georgia
The Weiss Lab at the University of Georgia's Complex Carbohydrate Research Center (https://ccrc.uga.edu/) is seeking a creative and enthusiastic postdoctoral fellow to drive research projects supported by a new NIGMS/NIH R35 award focused on investigating the regulation of glycosaminoglycan biosynthesis in human health and disease. These are multidisciplinary projects with enormous training opportunities in glycobiology, functional genomics, chemical biology, and drug discovery. The Weiss Laboratory utilizes a combination of biochemistry, cell biology and genomics to understand the structure, assembly and function of sulfated glycosaminoglycans found on proteoglycans. We utilize a number of techniques that offer high potential for training, including genome-wide CRISPR screening approaches, flow cytometry, mammalian cell engineering, and isolation and characterization of glycans. The postdoctoral fellow will be expected to design and evaluate experiments, develop new ideas and promote current research, and prepare and publish scientific manuscripts in collaboration with the Principal Investigator. The postdoctoral fellow may be responsible for the operation of scientific equipment and for teaching techniques to others, including training of students and supervision of research staff.
MINIMUM QUALIFICATIONS: Candidates must hold a Ph.D. in biochemistry, cell biology, genetics, or a related discipline. Preference will be given to candidates who have hands-on experience with CRISPR technologies and/or epigenetic/transcriptional techniques to study gene regulation. Excellent scientific writing ability and strong oral communication skills are required, as is the ability to work effectively with colleagues.
Interested applicants should send their CV and a list of 2-3 references to Dr. Ryan Weiss at ryan.weiss@uga.edu. Additional information is available at our lab website (https://weisslaboratory.com/).
Link:
https://www.ugajobsearch.com/postings/337288
Postdoc in Functional analysis of glycoproteins and glycosaminoglycans at Copenhagen Center for Glycomics
University of Copenhagen
We are offering 4 postdoc positions at the Copenhagen Center for Glycomics (CCG) with the Miller and Schjoldager Groups, commencing from 15 November 2023 – 1 April 2024 or after agreement.
2 positions are available in the Miller Group at CCG at the Department of Cellular and Molecular Medicine (ICMM) driving research projects:
Genetic dissection of a cell to produce therapeutic glycosaminoglycan structures.
Development of the next generation of analytical technologies to define the primary structure of a glycosaminoglycan chain.
In vitro and in vivo project in cardiovascular disease and inflammation.
More information at: https://icmm.ku.dk/english/research-groups/r-miller-group/.
Principal supervisor Associate professor Rebecca Miller (rmiller@sund.ku.dk).
2 positions are available in the Schjoldager Group at CCG at the Department of Cellular and Molecular Medicine (ICMM) driving research projects related to the discovery and dissection of biological functions of protein glycosylation with a focus on the identification of specific molecular functions of glycoproteins and glycoconjugates that impact human physiology and common diseases and dispositions to disease.
More information at: https://icmm.ku.dk/english/research-groups/schjoldager-group/.
Principal supervisor Associate Professor Katrine Schjoldager (schjoldager@sund.ku.dk).
Full advertisement and details can be found in the link below
https://employment.ku.dk/all-vacancies/?show=159932
Link:
https://employment.ku.dk/all-vacancies/?show=159932
Postdoc positions - Alzheimer’s disease
University of South Florida
Research Description
Two Postdoctoral associate positions are immediately available in the laboratory of Dr. Lianchun Wang lab in the Department of Molecular Pharmacology & Physiology and Byrd Alzhein Research Center, University of South Florida, Tampa, FL, USA. The Wang lab actively seeks to unravel the roles and the underlying mechanisms of heparan sulfate proteoglycan in Alzheimer's disease and other neurodegenerative disorders, through the utilization of human genetics data, mouse models, and a variety of cellular and biochemical approaches. Additionally, the lab is proactively striving to uncover novel mechanisms that can be targeted for therapeutic interventions against these diseases.
Link:
https://health.USF.edu/medicine/mpp/faculty/lianchunw
Post doc - autophagy
AIM center in a technologically advanced state
The hot fields of Canonical and noncanonical autophagy, the up an coming membrane Atg8ylation as a stress, damage and remodeling response
Link:
None
Postdoctoral fellow - cancer glycobiology
University of Hong Kong
Applicants should posses a PhD degree with solid hands on experience in molecular and cellular glycobiology of cancer and animal work. They should have a good command of written and spoken English, a strong sense of responsibility; good organisation skills; and the ability to work independently and handle multiple tasks.
Link:
awonglab.com
Postdoctoral Research Associate
University of Glasgow.
We are offering one postdoc position at the Centre for the Microenvironment (CeMI) with Dr. Miguel Pineda, commencing from January 2023. The project, ‘Investigating the role of synovial glycome in the interplay between systemic and local inflammation’ is MRC funded and will last for 3 years. The core goal will be to explore the role of fibroblasts’ glycome in perpetuation of chronic inflammation in Rheumatoid Arthritis and to correlate glycosylation signatures in stromal cells with clinical phenotypes, disease stages and development of associated comorbidities.
More information at: https://glasgow.thecemi.org, https://www.gla.ac.uk/schools/infectionimmunity/staff/miguelpineda/#
Key Words: Rheumatoid Arthritis, Inflammation, Glycomics, Immunity.
Principal supervisor Dr. Miguel Pineda (Miguel.pineda@glasgow.ac.uk)
Related publications:
Wang, Y. et al. (2021) Loss of α2-6 sialylation promotes the transformation of synovial fibroblasts into a pro-inflammatory phenotype in arthritis. Nature Communications, 12, 2343. (doi: 10.1038/s41467-021-22365-z)
Wang, Y., Pan, P., Khan, A., Çil, Ç. and Pineda, M. A. (2022) Synovial fibroblast sialylation regulates cell migration and activation of inflammatory pathways in arthritogenesis. Frontiers in Immunology, 13, 847581. (doi: 10.3389/fimmu.2022.847581)
Postdoc: Glycoengineering Biologics
Concordia University
https://www.concordia.ca/sgs/postdoctoral-fellows/funding/horizon/open-positions/14003.html
Link:
https://www.concordia.ca/sgs/postdoctoral-fellows/funding/horizon/open-positions/14003.html
Postdoctoral fellow - Glycan Biophysics
University of Leeds
The large, linear and regular polysaccharide hyaluronan (HA) is present in the extracellular matrix of all mammalian tissues, and exhibits an astonishingly broad array of functions in physiology and pathology. The ways in which the HA biopolymer is differentially organised through its interaction with proteins on the cell surface and in the extracellular matrix is key to the diversity of its biological functions. However, the underpinning molecular mechanisms are not well understood, due to the lack of tools to probe the complexity of HA/protein interactions. This project will generate a new toolkit required to reveal the biophysical phenomena underpinning HA/protein interactions and will open up new avenues for regenerative medicine.
The Research Fellow will deploy designer HA molecules with site-specific tags for anchorage and visualisation to develop biophysical assays capable of probing (i) how protein binding relies on HA chain orientation, topology and length, (ii) unconventional interaction modes such as one-dimensional sliding along the HA chain, and (iii) the mechanical response of supramolecular HA/protein complexes. The assays will improve our molecular understanding of HA-protein interactions relevant to immune and inflammatory responses, and tissue development, homeostasis and repair. The combination of method development and applications will provide exceptional career development opportunities for the interested applicant in the growing glycoscience and glycobiophysics areas.
To explore the post further or for any queries you may have, please contact:
Dr. Ralf Richter, Project Principal Investigator and Associate Professor (r.richter@leeds.ac.uk).
Link:
tinyurl.com/64pkwube
Glycoinformatics positions available
Soka University
Research assistants or post-doc positions available to participate in the national Human Glycome Atlas project at Soka University in Japan. Programming or server maintenance experience is required. Yearly renewable contract. Please email for details.
Link:
None
