Research Technician
Medical University of South Carolina
The Smith Lab will open in the Department of Neuroscience at the Medical University of South Carolina in December of 2021. There will be two technician position openings to start in December 2021 or early 2022. Our research will focus on identification of novel molecules that are likely to represent efficacious pharmacotherapeutic targets for treatment of drug addiction.
We will use rodent models of drug self-administration to examine the neurobiological substrates of addictive-like behaviors such as cue-induced reinstatement, escalation of intake, and continued use despite negative consequences. Following training of rodents in these models, we will perform high-throughput molecular brain imaging (e.g. iDISCO + light-sheet microscopy) to discover novel opioid-responsive brain regions & neurocircuitry, and molecular/biochemical methods (e.g. scRNA-Seq, immunoassays) to hone in on individual proteins and transcripts that may be efficacious targets for treatment of addiction. Furthermore, we will use advanced computational & statistical techniques (e.g. deep learning, linear modeling) for cutting-edge analysis of all experiments.
Applicants should have a Bachelor's degree in neuroscience (or a related life science) or bioinformatics (or a related computational science). As there are two positions available, no single candidate is expected to have experience in both 'wet lab' and 'dry lab' (computational) techniques, though there will be ample training opportunities for any technician to participate in any part of the research.
Interested candidates can contact me at alexander.smith@mssm.edu. Please provide a cover letter describing research interests and career goals, a CV, and the names and emails of 2-3 references.
Link:
None
Postdoc
UCSD
The George lab is seeking applicants for a postdoctoral position (Research Associate) available now. The successful applicant will receive training under NIAAA- and/or NIDA-funded research programs (R01/U01).
This solicitation seeks applicants who have an interest in neurobiological basis of drug, nicotine, and alcohol use disorders, including but not limited to the identification and characterization of the neuronal ensembles underlying compulsive alcohol drinking.
Candidates must have a PhD in neuroscience, pharmacology or biomedical sciences. Expertise with behavioral pharmacology and stereotaxic surgeries is higly recommended. Additional experience with patch-clamp electrophysiology, opto/chemogenetics, IV self-administration and brain imaging techniques are recommended.
An ability to think critically and creatively, along with strong writing and communication skills is essential. The successful candidate should be able to work independently and be willing to collaborate with the lab members and other groups in the Department of Psychiatry and Skaggs School of Pharmacy and Pharmaceutical Sciences.
Link:
http://www.oliviergeorge.com
Postdoctoral Fellowship: Molecular and cellular mechanisms of cognition in the hippocampus and prefrontal cortex in mouse models
Western University
The Translational Cognitive Neuroscience Lab at Western University (co-directed by Tim Bussey and Lisa Saksida) is looking for a postdoctoral researcher to undertake cutting-edge research in the area of brain mechanisms of cognition and behaviour. Our main behavioural approach involves touchscreen-based testing of mouse models, which allows us to assess many different aspects of high-level cognition in a way that is highly relevant to human patients. Touchscreen testing also facilitates reproducibility through increased standardization and reductions in experimenter and environmental influence. We subscribe to principles of open science, and promote data and knowledge sharing through mousebytes.ca and touchscreencognition.org.
This project is focused on molecular and cellular mechanisms of cognition in the hippocampus and prefrontal cortex, and will involve combining various neurotechnologies including fibre photometry recording and optogenetic manipulations with touchscreen-based cognitive assessment. The project is part of a collaboration between Western’s BrainsCAN and McGill’s Healthy Brains for Healthy Lives Canada First Research Excellence Fund initiatives and will involve opportunities for interaction across the two sites.
For more information: http://www.tcnlab.uwo.ca/join-us.html
Link:
http://www.tcnlab.uwo.ca/join-us.html
Postdoctoral Fellowship: Parvalbumin neurons and touchscreen-based assessment of cognition in mouse models
Western University
About this opportunity
The Translational Cognitive Neuroscience Lab at Western University (co-directed by Tim Bussey and Lisa Saksida) is looking for a postdoctoral researcher to undertake cutting-edge research in the area of brain mechanisms of cognition and behaviour. Our main behavioural approach involves touchscreen-based testing of mouse models, which allows us to assess many different aspects of high-level cognition in a way that is highly relevant to human patients. Touchscreen testing also facilitates reproducibility through increased standardization and reductions in experimenter and environmental influence. We subscribe to principles of open science, and promote data and knowledge sharing through mousebytes.ca and touchscreencognition.org.
This project is focused on developing an understanding of parvalbumin positive interneurons interact with neuromodulators including dopamine and acetylcholine in the service of aspects of cognition including attention, working memory and cognitive flexibility, and how disruptions in this system related to cognitive dysfunction in disorders such as schizophrenia. The work will involve combining various neurotechnologies including fibre photometry recording and optogenetic manipulations with touchscreen-based cognitive assessment.
For more information: http://www.tcnlab.uwo.ca/join-us.html
Link:
http://www.tcnlab.uwo.ca/join-us.html
Postdoctoral Fellowship: Perineuronal nets and touchscreen-based assessment of cognition in mouse models
Western University
About this opportunity
The Translational Cognitive Neuroscience Lab at Western University (co-directed by Tim Bussey and Lisa Saksida) is looking for a postdoctoral researcher to undertake cutting-edge research in the area of brain mechanisms of cognition and behaviour. Our main behavioural approach involves touchscreen-based testing of mouse models, which allows us to assess many different aspects of high-level cognition in a way that is highly relevant to human patients. Touchscreen testing also facilitates reproducibility through increased standardization and reductions in experimenter and environmental influence. We subscribe to principles of open science, and promote data and knowledge sharing through mousebytes.ca and touchscreencognition.org.
This project is focused on developing an understanding of how perineuronal nets-- components of the extracellular matrix that are primarily found wrapped around inhibitory, parvalbumin positive cortical neurons—contribute to adult learning and memory processes. This will be achieved by manipulating perineuronal nets in cortical regions critical for learning, memory and behavioural control, and/or manipulating levels of oxidative stress via diet, exercise, or environmental enrichment, and then assessing the mice on cognitive tests dependent on those brain regions.
For more information: http://www.tcnlab.uwo.ca/join-us.html
Link:
http://www.tcnlab.uwo.ca/join-us.html
Research Technician
University of Pittsburgh
The Kline laboratory at the Safar Center for Resuscitation Research at the University of Pittsburgh School of Medicine is seeking a highly motivated, organized, and detail-oriented individual for a full-time Research Laboratory Technician position with 2-3 yr commitment. The laboratory pursues a variety of behavioral, neurochemical, and molecular-based approaches to investigate motor and cognitive deficits, neurochemical alterations, and pharmacotherapies after experimental traumatic brain injury.
Techniques include motor and cognitive rodent tasks, Western blotting, tissue processing, immunostaining, and microscopy. The candidate will actively support the daily experimental work of the laboratory and will be responsible for lab organization, student training, and scheduling. He/she/they will be expected to have excellent communication skills, troubleshoot technical issues, and assist with statistical analyses and graphic presentation of data. Additional responsibilities include preparing reagents necessary for research, maintaining lab inventory, including timely ordering of required supplies. Dependability, great communication skills, and attention to detail are required. Under the supervision of the PI, the candidate is expected to work independently carrying out standard behavioral, molecular, and histological work. Experience with animal experiments is a plus, as well as willingness to learn new methods. The ability to effectively communicate with collaborators and co-workers is essential. Previous experience as research technician is not necessary, but some experience in a lab environment is preferred. Must have a proactive personality with an ability to learn new skills and techniques. Additionally, the candidate should be familiar with basic computing and data analysis software. Bachelor’s of science degree in neuroscience, psychology, biology, chemistry, or related field is required.
Link:
https://www.rehabmedicine.pitt.edu/people/ant-39
Tenure-Track Neuroscience Faculty Position
Univ South Carolina School of Medicine
The Department of Pharmacology, Physiology and Neuroscience at the University of South Carolina (UofSC) School of Medicine in Columbia, SC invites applications from outstanding neuroscience candidates for a tenure-track faculty position at the Assistant Professor level. New faculty members will join a highly successful, collegial, and collaborative neuroscience-focused department at a Carnegie R1 research university that has achieved national prominence in research, education, and community engagement. At UofSC, we strive to ensure an inclusive environment that is open, welcoming, and supportive of individuals of all backgrounds. The successful candidate is expected to complement departmental research strengths in studying fundamental mechanisms underlying neurophysiological processes, behavior, or drug action. Candidates expanding UofSC’s research prominence in the neural basis and treatment of neuropsychiatric, neurological, and stress-related disorders using preclinical models are encouraged to apply. Candidates will be expected to establish an innovative, externally-funded research program, mentor graduate students and postdoctoral fellows, and participate in graduate and medical education. Substantial start-up funds, laboratory facilities and access to core resources in imaging and functional genomics will be provided, as well as research opportunities with the Columbia VA Health Care System. For more information about the department visit: http://ppn.med.sc.edu/ . Qualified applicants must apply via USCJobs at https://uscjobs.sc.edu/postings/79721.
Link:
https://uscjobs.sc.edu/postings/79721
Postdoctoral Fellow
Icahn School of Medicine at Mount Sinai
The Karki Rajbhandari lab in the Department of Psychiatry and Neuroscience (Friedman Brain Institute) at the Icahn School of Medicine at Mount Sinai has an opening for full-time postdoctoral researcher. This institute-funded research in the Karki Rajbhandari laboratory focuses on understanding the brain and body mechanisms of stress and fear along with cardiorespiratory and energy metabolism functions. To probe these questions, we use a combination of behavioral assays, genetically targeted viral and transgenic mouse lines, immunohistochemistry, in situ hybridization, optogenetics or chemogenetics and confocal microscopy techniques. The lab is dedicated to a supportive, diverse and collaborative environment.
Qualified candidate should have a PhD in neuroscience, psychology, or a
related field. Candidates with animal behavior experiences, rodent surgeries, confocal imaging and molecular techniques are encouraged to apply. Interested candidate please email directly to abha.rajbhandari@mssm.edu with a description of research interests and experience along with a CV.
Duties and Responsibilities:
• Rodent viral surgeries at the level of brain regions and/or body organs
• Rodent behavior assays such as fear conditioning and open field
• Cardiorespiratory and metabolism measures
• Standard molecular biology techniques (PCR, recombinant gene cloning, immunohistochemistry, in situ hybridization)
• Preparation of reagents and solutions and buffers for experiments
• Animal handling, colony management, and genotyping
• Eager to learn new techniques, operate and manage lab equipment and personnel
Requirements:
• PhD in neuroscience, biology, psychology, or a related field
• Research experience in rodent behavior and surgeries
• Excellent organizational, problem solving and analytical skills
• Excellent verbal, written and interpersonal communication skills
• Knowledge of standard research concepts
Requirements:
PhD
Link:
https://careers.mountsinai.org/jobs/2705032?lang=en-us
Postdoc position
University of Florida
Jen Bizon and Barry Setlow have a newly-funded postdoc position in their labs to work on cognition, aging, and neuromodulation in rodent models. Opportunities for numerous other projects as well.
Postdoctoral Researcher
Joan C Edwards School of Medicine at Marshall University
The laboratory of Dr. Brandon Henderson in the Department of Biomedical Sciences in the Joan C Edwards School of Medicine at Marshall University is currently seeking a Postdoctoral researcher with a patch-clamp electrophysiology and neurobiology background, who will conduct and guide experiments defined in a funded NIH grant (R01 DA050717).
The experiments will be aimed at investigating how drugs of abuse alter midbrain neurons. Currently, the Henderson laboratory is focused on studying how these neurons are altered by nicotine and tobacco
flavorants. The principal scientific investigations include the monitoring of action potentials, whole-cell currents, and neural excitability in midbrain neurons. Please, refer to the Henderson lab website (www.hendersonlab.org) for additional information and references to relevant publications.
Apply Here:
https://marshall.peopleadmin.com/postings/16652
Link:
https://marshall.peopleadmin.com/postings/16652
Postdoc in Autism Research at MIND
UC Davis School of Medicine
Applications will be accepted at any time. Review dates will be based on the number of applications. Earliest review date: 2/28/22.
file:///var/mobile/Library/SMS/Attachments/cb/11/DEA4845A-42C7-44FA-8F86-4A96882008DF/IMG_0474.jpg
Start Date: September 1, 2022
Link:
https://health.ucdavis.edu/mindinstitute/education/postdoc_training/faculty.html
Postdoc - Neurobiology of Addiction
Medical University of South Carolina
The Smith Lab will open at the Medical University of South Carolina in December 2021, in the Department of Neuroscience. We will study the neurobiology of addiction, primarily using the cue-induced reinstatement model in both rats and mice, though other behavioral assays will commonly be used as well. I am currently funded by a K99/R00 (tinyurl.com/5ydnps94). We have used iDISCO+ and light-sheet microscopy in FosTRAP mice to identify brain structures that show robust induction of c-Fos following cue-induced reinstatement of oxycodone. Moreover, we have identified **highly** novel brain structures that display a tight correlation between c-Fos induction and lever-pressing behavior during a cued reinstatement test, which is not present in sucrose or saline controls. We will continue to use FosTRAP mice to express optogenetic constructs in these relapse-activated ensembles, and bidirectionally manipulate their activity to determine their roles in addictive behaviors. Furthermore, we will perform whole-brain circuit mapping from these regions by clearing the brains and using a light-sheet microscope that will be housed within our lab. We will also use single-cell and bulk RNA-sequencing to identify individual transcripts that are dysregulated by relapse behavior. During development of the K99/R00 I created a “preclinical pipeline” for target prioritization that, if successful, will lead to single molecules that are likely druggable targets for relapse prevention in humans. We will collaborate with the Department of Pharmaceutical Sciences at MUSC to aid in drug development and initiate human trials.
Please contact me at alexander.smith@mssm.edu with any questions, I am happy to set up a time to have a more detailed chat. To apply, please send a cover letter, CV, and names and contact info for 2-3 references to the above email.
Postdoctoral Fellow - Stress and Addiction
University of Cincinnati
A postdoctoral fellow position is available in the laboratory of Dr. Jayme McReynolds in the Pharmacology and Systems Physiology department at the University of Cincinnati College of Medicine. Research in our lab is centered on the effects of stress on the brain and behavior, with a focus on addiction. Current projects are using rodent models of cocaine self-administration to investigate the role of repeated daily stress on mesolimbic and prefrontal cortical circuits. We are using a variety of approaches including multiple behavioral models, fiber photometry, chemogenetics, neural tract tracing, immunohistochemistry, and transgenic rat models. There are a number of open projects to get involved in including examining the role of endocannabinoid signaling, sex differences, and neuroimmune and microglia changes in stress-induced escalation of cocaine intake. We have a fun and highly collaborative environment and will provide extensive mentorship and training. The University of Cincinnati has excellent resources and Cincinnati is a great place to live with a reasonable cost of living. If interested, please send a CV, list of 3 references, and a brief description of your current research to Dr. Jayme McReynolds at jayme.mcreynolds@uc.edu. If you have any questions about the position feel free to reach out.
Postdoctoral fellow
University of the Ryukyus
Neural circuits underlying dysfunction of social and repeated behavior in autism mouse models. 3yr term in Okinawa Japan
Link:
https://www.researchgate.net/profile/Hiroyuki-Arakawa
PhD student and Postdoc positions in social/systems neuroscience
Nencki Instutite of Experimental Biology PAS
We are seeking passionate and highly motivated PhD students and postdocs to work in the social/systems neuroscience project: "Coming together - neural dynamics of transition from out-group reserve to in-group fellowship".
Classifying individuals as members of an in-group, that is social circles with whom we identify, is a rapid and unconscious process. Consequently, very little is required to discriminate against the ones we identify as out-group, which happens on a similarly prompt and arbitrary basis, and oftentimes results in an unconscious bias. Arguably, it is because classifying individuals as either “us” or “them” is a hard-wired neuronal mechanism. We will investigate the role of the brain structure known to be key for encoding social familiarity in all tested mammalian species – prefrontal cortex.
We will conduct research focused on the neural underpinnings of overcoming reserve towards unknown conspecifics, in order to compose an amicable social group. We will apply a combination of cutting-edge techniques of systems neuroscience, including semi-naturalistic, automated behavioral assessment in transgenic mouse strains, two-photon microscopy in behaving animals, and chemo- and wireless optogenetics to discover how changes in the activity of the main cell types composing the circuits of the PFC involved in encoding social familiarity reflect the transition from out-group reserve to in-group fellowship.
Employment at the Nencki Institute of Experimental Biology, Polish Academy of Sciences, one of the top scientific research institutions in the EU.
Competitive salary rates! Start date subject to negotiation.
Interested? Please contact Alicja Puscian, PhD at a.puscian@nencki.edu.pl.
We are eager to hear from women and candidates from the underrepresented minorities. Please do not hesitate to reach out if you would like to know more about the project!
Link:
https://www.nencki.edu.pl/laboratories/laboratory-of-emotions-neurobiology/
Post doctoral associate at the Bravo Lab
University of Puerto Rico School of Medicine
We’re looking for motivated postdocs, preferably with expertise in single-unit or calcium imaging recordings. Our labs aims to characterize circuits mediating behavioral conflict between reward approach and punishment avoidance motivations, using different genetic mouse lines. We use the Platform-mediated avoidance task with different conflict contingencies together with cutting-edge recording approaches, optogenetics, chemogenetics. We are interested in characterizing different behavioral profiles, ranging from risky to avoidant profiles. We are also interested in understanding substrates of stress resiliency and susceptibility.
Pubmed: https://pubmed.ncbi.nlm.nih.gov/?term=bravo-rivera+c&sort=date
Current funding:
(https://reporter.nih.gov/project-details/9952906)
Link:
None
Post doc - Motivational Neuroscience at Rutgers University
Rutgers
The James lab at Rutgers (morganjameslab.com) is are currently seeking a motivated and enthusiastic postdoc to join our growing team. The candidate will work on a NIDA-funded project investigating the role of hypothalamic neuropeptide systems in drug (cocaine, opioid) use and binge eating disorder. We are especially interested in candidates with experience in molecular neurobiology approaches (PCR, Western Blots, RNA isolation, single-cell RNAseq/ATACseq etc). Opportunities for training include drug self-administration and behavioral modeling, chemogenetics, calcium imaging, optogenetics and viral-mediated anatomical tracing techniques. Candidates should hold a PhD, MD or equivalent (or be close to graduating), with experience in neuroscience, psychology, pharmacology or related disciplines. Most importantly, the candidate should be self-motivated, have strong oral and written communication skills (evidenced by a track record of publications) and above all, be a good lab citizen. We pride ourselves on offering an inclusive and supportive lab environment and we encourage applications by members of all backgrounds, including underrepresented groups.
Interested applicants, please reach out to Morgan James at morgan.james [at] rutgers.edu or on the Whova lab to discuss opportunities!
Link:
https://www.morganjameslab.com/
Postdoctoral Associate - Translational Research in Alzheimer's Disease
University of Pittsburgh
Exciting postdoctoral training opportunity using translational approaches for interrogating novel interventions that target the intersection of tau pathophysiology and neuroinflammation for the treatment of Alzheimer’s Disease.
The Rizzo laboratory at The University of Pittsburgh School of Medicine - Aging Institute is seeking an exceptional, ambitious, and highly motivated postdoctoral associate to join our growing laboratory. The lab investigates the progression of the pathophysiology of Alzheimer’s Disease and divergence from normal healthy aging, and uses preclinical model systems and translational approaches towards identifying disease and symptom-modifying therapeutics. The Rizzo lab is a critical component of several NIA-funded multi-institutional consortiums including the Model Organism for the Evaluation of Late Onset Alzheimer’s Disease (MODEL-AD) Center and the Alzheimer’s Disease Translational Centers for the New Medicines Drug Discovery Consortiums (TREAT-AD). This is an excellent opportunity for creative, motivated individuals interested in therapeutic drug development for Alzheimer’s Disease to make seminal contributions to the field in supporting preclinical evaluation of potential novel therapeutic interventions as part of these consortiums. The incumbent will be expected to lead an independent project utilizing multiple methods including genetics, mouse model development and phenotypic characterization, transcriptomics, protein biochemistry, and behavioral pharmacology techniques.
Qualifications: A PhD, MD, or MD/Phd required. The successful candidate will have excellent written and verbal English communication skills. Experience with mouse models, stereotaxic surgical techniques, protein biochemistry, and expertise in Alzheimer’s Disease is preferred.
Please email CV: rizzos@pitt.edu
Postdoc
SUNY Albany
Interested in how circadian rhythms shape behaviors? Keen on understanding its molecular and circuit underpinnings? This is the place for you! join a vibrant, multicultural, interdisciplinary team in Annalisa's lab at SUNY Albany (NY). We use patch-clamp, imaging, molecular and behavioral approaches to address these research questions. Please DM for more information.
Link:
https://sites.google.com/site/scimemilab2013/home
Postdoctoral Fellow
University of Regensburg
A full postdoctoral research position is available in the lab of Inga Neumann at the
Department of Behavioural and Molecular Neurobiology at the University of Regensburg (Bavaria) in September 2021 for up to 4 years. The candidate should have proven state-of-the-art methodological expertise in behavioural, molecular, neuroendocrine or neuronal network neuroscience in rodents (e.g., stereotaxic surgery, optogenetics, in vivo calcium imaging, or molecular methods in combination with cell culture). A good team spirit will help to accommodate easily in our international research group. As a young postdoc, you will first be integrated into an ongoing project, which will help you to develop as an advanced postdoc with the chance to follow your own scientific project. Our research is focused on neuronal, molecular including epigenetic regulatory mechanisms underlying emotional (anxiety, fear, depression-related) and social (social fear, aggression, social preference) behaviours in rats and mice especially in the context of regulation by neuropeptides (oxytocin, vasopressin, CRF) and their interactions. This position will be integrated into our PhD Graduate School “Neurobiology of socio-emotional dysfunctions” GRK 2174. With scientific projects at the interface of basic and applied neuroscience the offers an exciting career opportunity. Please send your application with CV, letter of motivation, publication list and the names of two referees to the address below. Deadline July 10th, 2021.
Link:
https://www.uni-regensburg.de/biologie-vorklinische-medizin/neurobiologie-tierphysiologie/team-mitarbeiter/prof-dr-inga-d-neumann/index.html
