Jobs Posted on the Whova Community Board of Serine proteases in pericellular proteolysis and signaling
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University of Sherbrooke I have an opening for a post-doctoral candidate to work on a Canadian Institute of Health Research funded grant to explore genetic and biochemical modulation of type II transmembrane serine proteases in disease states.
University of British Columbia Dr. Philipp Lange, Canada Research Chair in Translational Proteomics of Pediatric Malignancies and his team at the University of British Columbia (UBC) in Vancouver, Canada, seek an outstanding candidate with a recent PhD (<2years) and strong publication record with an exceptional passion to advance the fundamental understanding of proteome modulation in childhood cancer. This position is CIHR funded.
You will lead a project on the characterization and targeting of a new class of highly specific surface epitopes in childhood cancer. You will use new mass spectrometry approaches developed in our group to study the cell surface in primary pediatric cancer specimen and model systems and will use and advance cell biological and biochemical approaches to develop new modes to target and monitor malignant cells.
Research Team & Environment: Located at the BC Children’s Hospital Research Institute (BCCHRI), the leading pediatric research center in Western Canada, you will be embedded in the highly innovative and interdisciplinary research environment spanning BC Children’s Hospital, UBC and BC Cancer. Vancouver repeatedly ranks among the most livable places in the world and combines excellence in research with high quality of life. Excellent opportunities for personal and professional development are provided. You will be part of a dynamic team of experimental and computational scientists and embedded in the local BRAvE and national PROFYLE pediatric precision oncology initiatives where you will work with basic scientists, pathologists, analysts and clinicians. You will have direct access to state-of-the-art cell and molecular biology facilities, mouse and chicken chorioallantoic membrane (CAM) modeling platforms, mass-spectrometry, next-generation sequencing, flow cytometry, imaging and compute infrastructure.
More details at https://langelab.med.ubc.ca/open-positions/ or PM me.
Indiana University School of Medicine Positions for postdoctoral fellow, research associate and research assistant are available for candidates with previous experience in mouse models relevant to human diseases, preferably cardiovascular disease. We are looking for applicants with strong research background in transcriptional regulation/signaling pathways/non-coding RNAs using multiple experimental techniques including cell culture, RNA analysis, chromatin immunoprecipitation, performing mouse breeding, genotyping, and routine experiments such as cloning, Western blot, immunoprecipitation and immunohistochemistry analyses.
The PI has been funded by NIH & AHA grants. All eligible trainees have been also awarded AHA fellowships. Please visit the webpages below for his lab information, his detailed research interest, and his publications:
Washington University School of Medicine Description: Immediate opening for a postdoctoral appointment in the areas of medicinal, computational and synthetic organic chemistry. This exciting research project is focused on chemical biology and drug discovery including rational structure-based design, synthesis, and optimization of bioactive small-molecule inhibitors for the development of chemical tools and novel therapeutics targeting proteases, growth factors and cell-signaling pathways in cancer.
Requirements: Ph.D. in organic or medicinal chemistry with a strong publication record. Extensive experience with synthetic organic chemistry and use of modern techniques and instrumentation for purification and structural elucidation required. Ability to work independently, communicate data and results clearly coupled with strong analytical and problem-solving abilities are necessary. Experience with peptides, peptidomimetics and heterocyclic chemistry plus working in a collaborative team environment preferred. Computational docking and modeling experience is a huge plus.
Please submit applications enclosing a cover letter with copies of current curriculum vitae/resume and summary of research experience to: Dr. James W. Janetka, Washington University School of Medicine, 660 S. Euclid Ave., Box 8231, St. Louis, MO 63110, or email at firstname.lastname@example.org.
Computational protein engineer/designer
San Diego Startup If you have expertise using Rosetta design and MD simulations and would like to work with a new Biotech startup in the San Diego area, please get in touch ! Please pass on to anyone who might be interested. Note that you dont necessarily need to be in San Diego area.