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Jobs Posted on the Whova Community Board of Structural Birth Defects Trainee Symposium

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Postdoctoral Scientists & Lab Manager/Chief of Staff
Nationwide Children's Hospital
The Institute for Genomic Medicine (IGM) at Nationwide Children’s Hospital is creating a future that integrates genomics into the everyday practice of pediatrics. Led by a team of internationally-renowned genomic medicine scientists, IGM is housed in the campus’ newest research building, spanning ~25,000 square feet of laboratory and office space in a highly interactive setting.

We’re looking for a Postdoctoral Scientist and a Lab Manager/ Chief of Staff to join our Research Group to study the genetic basis of congenital malformations of the brain and the craniofacial tissues. Projects are focused on characterizing novel genes and variants identified through human whole genome sequencing. We use sequencing analysis as well as a range of molecular embryological tools, including genome editing in animal models and in vitro studies. Candidates will be expected to develop a vigorous research program in close consultation with the PI. Applicants with multiple first-author publications and experience in mouse genetics, bioinformatics, molecular biology and/or embryology are preferred. Our Postdoctoral Scientists are given a unique training opportunity, with a focus on helping the candidate to establish their career as an independent investigator.

This is an exciting opportunity for a recent PhD graduate or junior postdoc to develop their translational science and computational skills in a translational research setting, with opportunities to work on a diverse spectrum of projects which have a direct impact on pediatric patient care. Excellent verbal and written communication skills will be essential as the individual will work collaboratively with bioinformaticians, biologists, and clinicians on projects that lead to publications and presentations at professional meetings.


Penn/CHOP - Bhoj Lab Post Doc and Technician Openings!
Penn/CHOP
Bhoj Lab - Philadelphia, PA
We're looking for postdocs and/or technicians who are excited about developmental biology or neuroscience. We're a medium-size well-funded lab with an interest in rare genetic diseases, their causes, mechanisms, and targeted therapies. We work with mouse models, iPSC/organoids/patient cell lines, computational biology. We are within the Center for Applied Genomics, the largest pediatric biobank in the world and a leader in NGS technology. We're currently funded by NICHD, NINDS, NLM, Chan Zuckerberg, and over $1M in private donations. Please reach out to Elizabeth Bhoj - bhoje@chop.edu - for more information!
Link: https://www.research.chop.edu/bhoj-laboratory
Postdoctoral Fellow in Developmental Neurobiology
Richard Smith Lab
Richard S Smith Lab
Northwestern University
Feinberg School of Medicine
Pharmacology Department

We are building our research team and looking for applicants with a strong commitment to work in the developmental neurobiology field with a focus on mammalian brain development and human disease models. Current NIH funded projects are examining ion flux and biophysical properties of developing cell types in the prenatal brain, specifically as is relates to structural brain diseases in children. For more info please see www.rsmithlab.com.

As a postdoctoral trainee in the Smith lab you will gain expertise in human iPSC cerebral organoid model, single cell sequencing (transcriptome/ATAC), High-content confocal microscopy, ferret in utero hiPSC models, as well as physiology approaches (2-photon imaging, high-throughput electrophysiology, patch-clamp, calcium/voltage imaging).

Actively recruiting for NIH projects through 2026. Prospective applicants can send an email to richard.smith at northwestern.edu with a CV, cover letter, and list of 3 references.

Link: https://www.rsmithlab.com/
Postdoc Position - Vitamin Dependent Pathways Regulating Neural Crest Development
Baylor College of Medicine
The Poché Lab is seeking a highly motivated postdoctoral research associate/fellow with experience in mouse developmental genetics and embryology. This NIH R01-funded position is focused on studying the interplay between nutritional factors, such as vitamins, and genetic and metabolic pathways essential for embryonic development. Special emphasis will be given to neural crest-derived tissues. Our long-term goal is to use this information to devise new therapeutic strategies to modulate the development of neurocristopathies.

Preference will be given to candidates with a strong background in using genetic approaches to study either neural crest or cardiovascular development. This expertise should ideally include next gen sequencing (RNA-seq, ChIP-seq, ATAC-seq, single cell-seq, etc.) data analysis. However, training in these techniques can also be provided.

The Poché lab employs a multi-disciplinary approach utilizing genetic loss- and gain-of-function experiments, fate mapping, gene therapy, molecular biology, and live microscopy. In addition to technical training, all postdocs within the lab routinely receive one-on-one instruction in grant writing and presentation skills.

We are housed in the Department of Molecular Physiology and Biophysics at Baylor College of Medicine (BCM). Located in the Texas Medical Center, the largest medical center on the world, BCM postdocs have a tremendous amount of technical and intellectual resources at their disposal, including the 26 BCM Advanced Technology Core Labs https://www.bcm.edu/research/research-services/atc-core-labs.

In your application, please include a cover letter, current CV, and contact information for three references. Application review will begin immediately and will continue until the position is filled.


Link: https://www.bcm.edu/research/faculty-labs/ross-poche-lab
Postdoc Position - Retinal Regeneration
Baylor College of Medicine
The Poché Lab is seeking a highly motivated postdoctoral research associate/fellow with experience in retinal developmental biology, tissue regeneration, or transcriptome analysis. This NIH R01-funded position is focused on the study of the molecular mechanisms blocking mammalian Müller glial cell (MG)-mediated retinal regeneration. Our long-term goal is to determine whether the mouse retina retains latent regenerative potential, akin to other vertebrate species, and whether we can genetically “awaken” that potential to restore sight.

Special emphasis will be placed on the investigation of MG transcriptional reprogramming to a progenitor-like state. Preference will be given to candidates with a strong background in mouse genetics and in techniques to probe the transcriptome and epigenome. This expertise should ideally include next gen sequencing (RNA-seq, ChIP-seq, ATAC-seq, single cell-seq, etc.) data analysis. However, training in these techniques can also be provided.

The Poché lab employs a multi-disciplinary approach utilizing genetic loss- and gain-of-function experiments, fate mapping, gene therapy, molecular biology, and live retinal confocal microscopy. In addition to technical training, all postdocs within the lab routinely receive one-on-one instruction in grant writing and presentation skills.

We are housed in the Department of Molecular Physiology and Biophysics at Baylor College of Medicine (BCM). Located in the Texas Medical Center, the largest medical center on the world, BCM postdocs have a tremendous amount of technical and intellectual resources at their disposal, including the 26 BCM Advanced Technology Core Labs https://www.bcm.edu/research/research-services/atc-core-labs.

In your application, please include a cover letter, current CV, and contact information for three references. Application review will begin immediately and will continue until the position is filled.
Link: https://www.bcm.edu/research/faculty-labs/ross-poche-lab
Postdoctoral Position Transcriptional and Epigenetic Control of Organ Morphogenesis in Development, Evolution, and Disease
University California San Francisco
Positions for highly motivated postdocs are available in the laboratory of Dr. Licia Selleri in the Institute for Human Genetics of the University of California, San Francisco. We study the epigenetic and transcriptional regulation of morphogenesis in development, evolution, and disease. To this end, we use genome-wide, systems biology approaches coupled with in vivo imaging, leveraging the strengths of different organismal systems, including mouse, chick, pig, and human embryos. A special focus is on organogenesis of the craniofacial & appendicular skeleton.
The project for the available position will be aimed at understanding the cellular, genetic, and regulatory mechanisms underlying face morphogenesis using mouse and human embryos. The successful candidate will also have the opportunity to participate in an ongoing collaboration with the group of Dr. Axel Visel at the Lawrence Berkeley National Laboratory (LBNL), based on a recently funded collaborative R01 grant focused on the characterization of enhancer variants, identified at the single-cell resolution, which are associated with human craniofacial malformations.
Candidates must hold a PhD degree in genetics, molecular biology, biochemistry, or relevant field. The ideal candidate should have strong interests in gene regulation in morphogenesis and/or evo-devo. Bioinformatic skills and experience in next generation sequencing are desirable. Our lab is located within the stimulating scientific environment of UCSF on the Parnassus within one of the strongest US communities devoted to the study of craniofacial development, the UCSF Program in Craniofacial Biology. Our group has also established collaborations with other outstanding laboratories that focus on craniofacial development in the Bay Area, both at Stanford and at the LBNL.
It is of note that the UC system recently adjusted its compensation guidelines to provide competitive postdoc salary.
Interested applicants should contact: Licia.Selleri@ucsf.edu
Tenure Track Faculty Position at the University of Chicago
The University of Chicago

The University of Chicago's Department of Pediatrics invites applications at any rank for tenured or tenure-track faculty members whose research in any field, including genetics, genomics, immunology, or neuroscience, has relevance to child health. We are very interested in the genetics and genomics of developmental defects!
Feel free to contact me with questions - Thank you, Ivan Moskowitz
Link: https://apply.interfolio.com/96386
Postdoctoral position in the Moskowitz laboratory at the University of Chicago
University of Chicago
Exciting opportunity in the Moskowitz laboratory to drive a research project in developmental biology aimed to understand the molecular basis of birth defects. We have recently identified a surprising and novel role for Hedgehog signaling in developmental timing control that will be the basis of future projects (Rowton et al. 2020). (https://www.biorxiv.org/content/10.1101/270751v3).
Please e-mail me with any questions. Thank you, Ivan
Link: https://www.biorxiv.org/content/10.1101/270751v3
Postdoctoral position Bennett lab Seattle Childrens Research Institute
Seattle Chldrens Research Institute
Seeking a postdoc to oversee our “HiddenSeq” project, which focuses on novel methods to identify genetic variation in pediatric structural birth defects that is not detected by standard, blood based, short-read DNA sequencing. Using already established cohorts of individuals with vascular malformations as well as ongoing recruitment of individuals with other types of structural birth defects, we aim to show that a great deal of pathogenic genetic variation is missed by current standard of care (blood based exome or genome sequencing) methods. The lab is highly translational with direct interaction with the clinicians managing individuals with these diseases.

If you are interested in joining our young and growing team please email the following documents to the PI directly (jtbenn@uw.edu).

1) current CV (including contact information of 2 or more references)
2) brief description of your past and future research interests


Link: http://depts.washington.edu/cdbrm/wordpress/research-labs/bennett-lab/
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