Postdoctoral researcher
Royal Veterinary College
Creating genetically-accurate models of CLN3 disease in zebrafish. Not yet officially advertised
Postdoctoral fellowships
Pediatric Storage Disorders Laboratory
Postdoctoral fellowships are available in the Pediatric Storage Disorders Laboratory, Washington University in St Louis to study and treat new aspects of disease in NCL mouse and sheep models. Using functional and behavioral tests, histology, quantitative microscopy, pre-clinical translation (enzyme replacement, gene therapy). For further information please contact Dr. Jonathan Cooper via cooperjd@wustl.edu
Postdoctoral scientist (junior/senior)
Penn State College of Medicine
We study how organelle crosstalk between mitochondria and lysosomes contributes to cell function and disease (including lysosomal storage diseases like Batten disease). My lab has two funded positions for postdoctoral scientists, one junior and one senior. We seek scientists that are interested in metabolism, organelle crosstalk, and signaling mechanisms of disease.
Experience in any of the following is a plus: imaging, RNAseq analysis/bioinformatics, neurobiology, iPSC differentiation is a plus.
The project involves cultured mammalian cells (including some CRISPR new lines we generated), iPSC-derived cells, and mouse models, and often builds on in silico data to generate testable hypothesis.
The position is initially offered for one year due to university rules, but is renewable.
Some of our recent papers:
Fernandez-Mosquera et al (2019) Autophagy 15: 1572-1591
Yambire et al (2019) eLife 8:e39598
Yambire et al (2019) eLife 8:e51031
Fonseca et al (2019) Nature 570: E34-E42
Deus et al (2020) Trends Mol Med 26: 71-88
Gowrisankaran et al (2021) Nature Communications 11: 1266
Sathyanarayanan et al (2021) Nature Communications 11: 5226
Deus et al (2021) Redox Biology 45: 102037
If interested, please email for more information: nuno.raimundo@psu.edu
Link:
https://psu.wd1.myworkdayjobs.com/en-US/PSU_Academic/job/College-of-Medicine/Postdoctoral-Scholar_REQ_0000019400
Postdoctoral researcher
Trent University
Using Dictyostelium discoideum as a model system for studying NCL proteins
Link:
http://huberlab.ca
Postdoctoral researcher
University of Rochester
NIH funded position focused on understanding the molecular basis of vision loss in CLN3-Batten.
Link:
None
Senior Clinical Fellow in Paediatric Neurology
The Evelina London Children's Hospital
The successful candidate will be exposed to a wide variety of neurological conditions both acute and chronic in both the outpatient and inpatient settings. The post will offer opportunities to develop skills in multidisciplinary management of childhood neurology and in the use and interpretation of neuro-imaging methods, and neurophysiological tests. A large number of multidisciplinary clinics also take place, which provide further components towards neuro-disability and general neurology exposure. They include complex epilepsy, neuromuscular and peripheral neuropathy, and neonatal neurology
Link:
https://www.guysandstthomas.nhs.uk/careers/our-vacancies.aspx#!/job/UK/London/London/Guys_St_Thomas_NHS_Foundation_Trust/Paediatric_Neurology/Paediatric_Neurology-v3516339?_ts=352
Research Coordinator - Clinical Trials Unit
Kennedy Krieger Institute
Research Coordinators in the Clinical Trials Unit collaborate with Principle Investigators (PIs) and research teams to conduct clinical research, including clinical trials. This position requires a degree of responsibility, flexibility, and independence to perform diverse duties including operationalizing protocols, and collecting, analyzing, and archiving data.
Link:
https://jobs-kennedykrieger.icims.com/jobs/16926/research-coordinator---clinical-trials-unit/job
Senior Research Coordinator - Clinical Trials Unit
Kennedy Krieger Institute
The Senior Research Coordinator in the Clinical Trials Unit will be primarily responsible for complex project management for multiple research studies related to neurological and neuropsychiatric conditions in pediatric patients. Activities include but are not limited to project execution, implementation, daily administration and close out for multiple research studies. The Senior Research Coordinator will ensure precise implementation of and adherence to study protocol, create all study documentation, oversee operating procedures, timelines, IRB applications, data preparation, and other research-related activities. In addition to operational management of multiple research studies, the Senior Research Coordinator will see participants in ongoing clinical trials, and will be responsible for specimen collection, processing, and DOT/ IATA compliant handling and shipment.
Link:
https://jobs-kennedykrieger.icims.com/jobs/16233/senior-research-coordinator/job
Head of Gene Therapy
Tevard Biosciences
Tevard Biosciences, an exciting company co-founded by renowned MIT molecular cell biologist Harvey Lodish developing novel tRNA based gene therapies for rare diseases, is seeking a Head of Gene Therapy, based in Cambridge, MA.
As the Head of Gene Therapy, you will report directly to the CSO and be responsible for defining and executing our gene therapy strategy and lead research teams to develop life-changing therapies for patients with severe genetic disorders. You will lead the company’s development of innovative tRNA payloads delivered through AAV vectors and lead a team of highly talented scientists responsible for constructing and producing novel therapeutic candidates for research and developing and optimizing them for clinical trials. You will be expected to manage the career development and performance of the existing team and recruit top talent.
Link:
https://tevard.com/#careers
Sr Research Associate/Research Scientist - AAV Production
Tevard Biosciences
Tevard Biosciences, an exciting company co-founded by renowned MIT molecular cell biologist Harvey Lodish developing novel tRNA based gene therapies for rare diseases, is seeking a Sr. Research Associate/Scientist - AAV Vector Production, based in Cambridge, MA.
In this role, you will work with cross-functional teams to generate AAV vectors in support of Tevard’s preclinical pipeline and novel tRNA-based therapeutic platforms. The role encompasses a diverse set of responsibilities and will enable the individual to take part in developing life-changing gene therapies for patients with severe genetic disorders. The ideal candidate will have a background in upstream and downstream AAV processes in an industry setting or academic vector
core. Applicants must be highly-motivated and comfortable working in a fast-paced, start-up environment.
Link:
https://tevard.com/#careers
Postdoctoral Fellow Position NICHD, NIH
NICHD, NIH
Looking for a PDF interested in development of therapies for rare diseases. Including Smith-Lemli-Opitz syndrome, Niemann-Pick Disease type C and CLN3 disease. Laboratory utilizes various model systems including iPSCs and mouse models. Techniques range from proteomics to scRNA seq.to high throughput drug screens. Goal is to understand pathological processes as well as identification and testing of potential therapies. We have a complimentary clinical research group that supports a biomarker discovery effort.
