Senior Research Associate
OHANA biosciences
Ohana Biosciences is seeking an innovative and highly motivated Senior Research Associate with expertise in cell and molecular biology and assay development to play a vital role in the company’s efforts to advance the field of reproductive medicine.
At Ohana Biosciences, the Senior Research Associate will have wide-ranging responsibilities and tremendous opportunities within a dynamic, enthusiastic, highly interdisciplinary, and collaborative team.
Ohana is pioneering a new frontier in reproductive medicine. Built upon a world-leading understanding of sperm biology, Ohana has created a best-in-class proprietary platform with broad applications across reproductive medicine. Ohana is developing field defining new products to improve sperm quality and function to address infertility, prevent inherited disease, and produce a long-acting, reversible, non-hormonal male contraceptive.
What You’ll Do
Work both independently and as part of a collaborative team to design, plan and execute experiments that support research activities, project goals, and platform development
Serve as a key contributor to the development of new technologies in reproductive medicine
Implement existing Ohana technologies and develop novel assays with little or no supervision
What Skills You’ll Bring
Bachelor’s or Master’s degree in a biological science or related science field.
3-5 years (Master’s) or 7-10 years (Bachelor’s) in the bio-pharmaceutical industry
Proven hands-on experience with cell-based and biochemical assays with a variety of readout technologies, such as, but not limited to: flow cytometry, Western Blot, ELISA, and immunofluorescence
Hands-on experience in cell culture and characterization of cells from human and animal tissues
Experience with independently generating and analyzing data, including basic statistical analyses
Familiarity with binding assays (SPR or related techniques) to determine antibody affinity
Experience with transiently expressing re
Link:
https://www.linkedin.com/company/ohana-biosciences-inc
Scientist/Senior Scientist, Assay Development
OHANA biosciences
The Assay Development Scientist/Senior Scientist will play a key role in establishing medium to high-throughput screening assays for human sperm, supporting Ohana’s mission of transforming reproductive medicine. Planned readouts include calcium and potassium flux, changes in motility, hyperpolarization, flow cytometry and immunofluorescence. Experience with designing novel experimental strategies and cell-based assays compatible with medium to high-throughput formats is necessary. Close collaboration with project teams to develop solutions for improving the throughput of challenging assays is key for this role. In addition, this individual should thrive in a fast-paced and demanding startup environment.
Ohana is pioneering a new frontier in reproductive medicine. Built upon a world-leading understanding of sperm biology, Ohana has created a best-in-class proprietary platform with broad applications across reproductive medicine. We are developing field-defining new products to improve sperm quality and function to address infertility, prevent inherited disease, and produce a long-acting, reversible, non-hormonal male contraceptive.
What You’ll Do
Establish medium to high-throughput screening assays for human sperm.
Design novel experimental strategies and cell-based assays compatible with medium to high-throughput formats.
Work closely with project teams to develop solutions for improving the throughput of challenging assays.
What Skills You’ll Bring
Ph.D. in Biology, Biochemistry, Cell Biology or related science and at least three years of post-doctoral experience, preferably in the bio-pharmaceutical industry.
Demonstrated technical expertise in multiple cell biology and biochemistry techniques including flow cytometry, fluorescence microscopy, and plate-based assays.
Technical leadership in cell-based functional assays, with the ability to design, develop and execute assays from inception through validation. Accoun
Link:
https://www.linkedin.com/company/ohana-biosciences-inc
Antibody Protein Engineer
Ohana biosciences
This role is an exciting opportunity to make a highly impactful contribution to the success of Ohana Biosciences. This individual will design engineering strategies to develop multispecific antibodies and affinity-mature and humanize antibodies. He/she will use display technologies (phage/yeast) or high-throughput transient expression methods as a tool to screen the engineered candidates and also contribute to campaigns for novel antibody discovery. Candidates should have a strong background in protein design preferably with antibodies. They will contribute to the execution of experiments in the laboratory and also be expected to manage at least one research associate. Close collaboration with project teams to develop solutions for intriguing scientific questions is key for this role.
Ohana is pioneering a new frontier in reproductive medicine. Built upon a world-leading understanding of sperm biology, Ohana has created a best-in-class proprietary platform with broad applications across reproductive medicine. We are developing field-defining new products to improve sperm quality and function to address infertility, prevent inherited disease, and produce a long-acting, reversible, non-hormonal male contraceptive.
What You’ll Do
Design engineering strategies to develop multispecific antibodies and affinity-mature and humanize antibodies
Use display technologies (phage/yeast) or high-throughput transient expression methods as a tool to screen the engineered candidates and also contribute to campaigns for novel antibody discovery
Contribute to the execution of experiments in the laboratory and manage at least one research associate
Collaborate closely with project teams to develop solutions for intriguing scientific questions
What Skills You’ll Bring
Ph.D. in Biology, Biochemistry, Bioengineering, Structural Biology or related science
Demonstrated track record in successfully humanizing and affinity maturing antibodies
Significant experience with protein mod
Link:
https://www.linkedin.com/company/ohana-biosciences-inc
Research Associate, Epigenetics
Ohana biosciences
https://www.ohanabio.com/careers/researchassociateepigenetics
Link:
https://www.linkedin.com/company/ohana-biosciences-inc
scientist cell biology
Ohana biosciences
https://www.ohanabio.com/careers/scientistcellbiology
Link:
https://www.linkedin.com/company/ohana-biosciences-inc
scientist molecular biologist
Ohana biosciences
https://www.ohanabio.com/careers/scientistmolecularbiology
Link:
https://www.linkedin.com/company/ohana-biosciences-inc
head-of-clinical-operations
Ohana biosciences
https://www.ohanabio.com/careers_head-of-clinical-operations
Link:
https://www.linkedin.com/company/ohana-biosciences-inc
Senior Director of Program and Portfolio Management
Ohana biosciences
https://www.ohanabio.com/careers/seniordirector
Link:
https://www.linkedin.com/company/ohana-biosciences-inc
Postdoctoral position
Stern college, Yeshiva University
A postdoctoral position in the field of testes biology is expected to be available from the late summer/ fall of 2019. Interested candidates must have experience in mouse genetics. Experience in the field of spermatogenesis is an advantage.
Link:
None
Postdoctoral Fellow/Research Associate – Molecular Diagnostics
CReATe Fertility Centre
Research program in top-rated fertility clinic setting seeks enthusiastic candidate to collaboratively undertake the investigation of idiopathic male infertility, discovery of biomarkers, investigation of extracellular vesicles (EVs) and EV-contained nuclear acids and proteins associated with male fertility and development of molecular diagnostics. The candidate will collaborate with other research groups and provide technical expertise in EVs isolation and characterization, proteomics, molecular biology of male infertility.
Link:
www.createivf.com
Post Doctoral Position - Travis Lab
Cornell University
An NIH-funded, post-doctoral associate position is available in the lab of Alexander Travis. The successful candidate will use multidisciplinary approaches including cell and molecular biology, advanced imaging and microscopy, biochemistry and mouse genetic models to investigate membrane regulation of ion channels in various cells. Understanding how the membrane lipid and protein microenvironment regulates channel activity will improve our understanding of normal physiological events such as fertilization, as well as pathological conditions such as obesity, diabetes and infertility.
Qualifications: Ph.D. in related fields. Experience with cell and molecular biology, biochemistry, cell culture, and work with lab animals is desired. Experience with ion channel physiology, electrophysiology, and lipids will be considered favorably. Effective written and verbal communication skills are essential for participating in our multi-disciplinary team, and writing scientific papers and grant proposals. Strong work ethic, creativity, enthusiasm, and ability to work in a team are required.
Full-time, 2 year appointment with possible extension depending on funding and performance.
Interested candidates should submit a cover letter describing your background, interests and career goals, and a CV including names and contact information for three references at AcademicJobsOnline posting # 13240 (https://academicjobsonline.org).
If you have questions about the position please contact Dr. Roy Cohen: rc338@cornell.edu.
Cornell University is an Affirmative Action, Equal Opportunity Employer and Educator.
Link:
https://academicjobsonline.org
postdoc in Nanjing, China
Nanjing Medical University
Postdoctoral positions open in Nanjing, China
State Key Laboratory of Reproductive Medicine at Nanjing Medical University has several positions open for postdoctoral fellows. Interested persons please send CV to xuyujun@njmu.edu.cn and exu2011@gmail.com
The compensation is competitive and Nanjing is a vibrant city with long history of being capitals for several dynasties. It is only one-hour train ride away from Shanghai, easily accessible via international direct flights to many cities of North America and Europe.
State Key Laboratory is the only State Key Laboratory in Reproductive Medicine under Ministry of Science and Technology of China
Link:
https://doi.org/10.1093/nsr/nwy163
Postdoctoral fellow - sperm epigenetics in Pilsner lab
University of Massachusetts Amherst
Postdoctoral research associate positions are available immediately to work on three NIH-funded projects on the role of preconception environmental exposures on sperm epigenetics and early-life development at the University of Massachusetts Amherst. The first project relates to population-based study, Sperm Environmental Epigenetics and Development Study (SEEDS), which has been enrolling couples seeking in vitro fertilization (IVF) to understand the associations between paternal exposures to endocrine disrupting compounds (EDCs), such as phthalates, sperm epigenetics, and embryo development. The second project parallels our human research in a mouse model by investigating the embryonic inheritance of sperm epigenetics after adult environmental exposures. These projects will utilize a variety of locus-specific and next-generation sequencing techniques such as RNA-seq, RRBS and WGBS in mouse sperm and embryos. Opportunities for postdoc-driven independent research are also possible.
Qualifications: A PhD in Molecular Biology, Biochemistry, Cellular Biology, Genomics, Environmental Health Sciences or a related field and a strong publication record are required. Candidates must have a strong background in epigenetics, male reproductive biiology, next-generation sequencing, and computational biology/bioinformatics. A candidate with both wet bench next-generation sample preparation and computational biology experiences is preferred. Experience in chromatin biology and/or environmental toxicology is preferred but not required. The successful candidate will be expected to work independently on projects, generate and analyze data, help graduate students, and write manuscripts.
For more information contact Dr. Richard Pilsner via email at rpilsner@umass.edu or www.pilsnerlab.com
Link:
www.pilsnerlab.com
