Jobs Posted on the Whova Community Board of What Can You Be With a PhD?
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Analyst / Consultant
Acsel Health Acsel Health is a consulting firm that partners with renowned life science companies to guide life-changing innovations through their critical stages, from early development through market maturity.
This is where your passion, perseverance, and past experience will converge in unique perspective that ignites your teams and inspires your clients. If you are a sharp thinker, fast learner, and great storyteller, come build your career with us. We are hiring experienced talent at all levels.
Primary Responsibilities -Conduct advanced secondary research and primary research proficiently -Analyze data and identify relevant insights -Provide substantiated input to development of strategic recommendations -Acquire industry knowledge and establish key experience -Actively manage projects and maintain close communication with the team and clients
Application: Immediate paid internships and full-time opportunities available. Please submit your cover letter and resume to firstname.lastname@example.org or email@example.com, and mention your participation in WCUB 2021.
Scientist/Senior Scientist- Myeloid Cell Biology
Arcus Biosciences Summary
The Biology team is seeking an energetic and highly motivated myeloid cell biologist to develop new therapies for various disease settings, with a primary focus on cancer. Scientists at Arcus work closely with colleagues within their team and across the organization in a highly collaborative environment that fosters the development of transformational therapies for cancer patients. The successful applicant will be expected to provide in-depth knowledge, technical expertise, and insights into myeloid cell biology as it relates to Arcus drug development programs
Candidates will be expected to work effectively in an interdisciplinary team to deliver time-sensitive objectives for drug discovery projects. Scientists will contribute intellectually as well as experimentally to plan and conduct experiments, interpret the results, and present their findings in both internal and external forums. These contributions will be utilized routinely to devise and implement a variety of in vivo and in vitro model systems to build an in-depth understanding and biological dataset surrounding Arcus drug targets and drug candidates.
PhD in immunology or immuno-oncology with an emphasis on dissecting the mechanisms of myeloid cell activity (postdoctoral training is a plus). For Sr. Scientist applicants, at least 3 years of drug discovery experience in a high-quality industry environment is required. A demonstrated ability to advance scientific projects as evidenced by consistent publication of peer-reviewed journal articles and presentations or posters at scientific conferences A strong understanding of current literature on myeloid cell biology and its implications for immuno-oncology. Familiarity with bioinformatic databases to understand immune activity is preferred. Experimental proficiency in various aspects of myeloid cell biology, including but not limited to: Methods to isolate, differentiate, and stimulate primary myeloid cells from
Scientist/Senior Scientist- T Cell Biology
Arcus Biosciences Summary
The Biology team is seeking a highly motivated T cell biologist to work closely with colleagues within the team and across the organization to discover and develop new therapies for various disease areas, with a primary focus on cancer.
The successful applicant will be expected to provide in-depth knowledge, technical expertise, and insights on T cell biology as it relates to Arcus drug development programs. These qualities will be utilized routinely to devise and implement a variety of relevant in vivo and in vitro model systems. These models will be used to build an in-depth understanding and biological datasets surrounding Arcus drug targets and drug candidates. Scientists will contribute both intellectually and experimentally as part of a multidisciplinary team, routinely collating and presenting data in both internal and external forums.
PhD (postdoctoral training is a plus) in immunology or a closely related field Candidates with pipeline drug development experience are highly sought (position title would be commensurate with years of relevant experience) Intellectual and experimental proficiency in various aspects of T cell biology gained through demonstrated research experience. Ideally this proficiency would include: A foundational knowledge of T cell subsets and cell surface-marker phenotypes Familiarity with current literature on T cell biology in cancer/immuno-oncology, including wet-lab and bioinformatic-based approaches to study T cells Expertise related to common immunological assays, including 10+ parameter flow cytometry panel design and implementation of methods to assess T cell functionality Practical experience developing and/or interrogating murine disease models (preferably tumor models), culturing of primary cells (mouse and human), using common molecular techniques, and developing cell-based assays A clear track record of productivity as evidenced by consistent publication/presentation record
Arcus Biosciences is an exciting growth company founded on the vision of creating best-in-class cancer therapies. We leverage our deep cross-discipline expertise to discover highly differentiated therapies and combinations to address unmet medical needs.
We have an excellent opportunity for a Scientist/Associate Scientist to join our growing Protein Sciences group. This role is expected to conduct lab work to support assay development, high throughput screening, structural biology, and interact closely with others within the research organization.
Responsible for supporting multiple programs with protein reagents Independently design constructs, optimize protein expression, and purify protein
PhD in Molecular Biology, Biochemistry, Structure Biology or other related field with 0-3 years industry experience or Master's/Bachelor's degree with multiple years of experience. Title will be commensurate with experience. Expertise in molecular biology techniques such as construct design, DNA isolation, cloning, and vector engineering for protein expression Extensive experience in diverse expression systems including microbial, insect and mammalian cells for protein expression Technical proficiency in purifying proteins using batch or column-based purification methods using AKTA FPLC Hands-on experience running protein analytical assays including SDS-PAGE, Western blot, HPLC, DSF Ability to multi-task and work flexibly with a high sense of urgency in a cross-functional team environment Strong communication, organizational and interpersonal skills
Senior Program Officer
Foundation for Opioid Response Efforts Reporting to the President, the Senior Program Officer (SPO) is a newly created position and will be an addition to an existing program team of senior program officer and program associate. This new member will be responsible for building upon our established programmatic infrastructure by further developing, implementing, and coordinating grantmaking strategies and for advancing strategic and operational objectives of program areas. These grantmaking activities include developing and implementing Requests for Proposals (RFP) and managing the selection process, reviewing, and analyzing proposals, writing recommendations for funding, monitoring grant performance, serving as the primary contact and developing strong working relationships with grantees. The Senior Program Officer will research new program areas and potential grantees and participate in value-added activities such as convenings of experts and development of resources. The SPO will work collaboratively with administrative and program staff to ensure fiscally sound grant making; and will work closely with the President, program staff, and communications team on communications strategies.
More details and how to apply can be found at the link below.
Cancer Research Institute The role offers this high-performing individual an opportunity to work in a well-capitalized nonprofit organization and to lead work that will have direct impact on the development of potentially curative treatments for all types of cancer. They will be able to collaborate with Cancer Research Institute (CRI)’s scientific leadership as well as pharmaceutical, biotechnology, and clinical trial management partners. The individual will also be able to stay on top of key immunotherapy trends and developments in oncology.
The Research Analyst will be an integral team member of one of CRI’s flagship programs, the Clinical Accelerator—a unique global collaboration of more than 80 of the field’s top clinical researchers and over 20 top biopharma companies designed to identify novel combinations of cancer immunotherapies that may hold transformational promise for patients (https://www.cancerresearch.org/scientists/clinical-accelerator). The program provides philanthropic investment and clinical resources to accelerate the clinical development of CRI-supported clinical studies.
Working closely with the Clinical Accelerator’s leadership, the successful candidate will be an integral part of the program’s scientific diligence efforts, including: • Reviewing and evaluating scientific posters, publications, websites, and confidential preclinical/clinical data from companies • Attending and reporting on scientific/industry conferences and medical meetings • Monitoring clinical trial designs, drug development plans, and correlative research strategies • Assisting in generating new, field-wide analyses that will help guide the evolution of CRI’s overall program strategies • Assisting in updating the Clinical Accelerator’s IO landscape database and publication of the update • Assisting in completing ad hoc consulting assignments • Collaborating with team members and partners on the publication of research in leading academic or trade journals as well
Scientific Editor, iScience
Cell Press Cell Press is looking to expand the team of scientific editors working on iScience, an exciting broad scope open access journal publishing in the life and physical sciences.
We are seeking to add a dynamic and enthusiastic Scientific Editor, who shares our passion for helping scientists publish their work in a straightforward and timely way. Priority will be given to candidates with a physics background, and to candidates with demonstrable skills in managing an academic Editors or Special Issues program.
Scientist, Computational Biology
GC Therapeutics GC Therapeutics is seeking a talented and highly motivated Scientist/Senior Scientist for our Single Cell Genomics team. The candidate will have strong expertise in single cell genome-scale assays from both experimental and computational approaches. The candidate will be responsible for the analysis and interpretation of genome-scale datasets (RNA-seq, single-cell RNA-seq, whole genome sequencing), a major area of interest at the GCTx. The job requires innovative problem solving in all parts of the process from sequencing, estimating gene and transcript expression, applying statistical methods for dimensionality reduction, differential analyses and clustering, to biological interpretation and multimodal data integration. Reporting to the Head of Discovery Platforms, this individual will apply these assays to develop novel cell therapies derived from human induced pluripotent stem cells (iPSCs) for regenerative and cell-based therapies. This role will involve bringing a new class of cellular therapies to patients using GCTx’s TFome™ platform, a synthetic biology-driven technology to differentiate human stem cells.
Scientist, Stem Cell Biology
GC Therapeutics GC Therapeutics is seeking a talented and highly motivated Scientist for our Stem Cell team. The candidate will have strong expertise in human pluripotent stem cell biology. Reporting to the Head of Discovery Platforms, this individual will engineer novel cell therapies derived from human induced pluripotent stem cells (iPSCs) for regenerative and cell-based therapies. This role will involve bringing a new class of cellular therapies to patients using GCTx’s Human TFome™ platform, a synthetic biology-driven technology to differentiate human stem cells. The scientist will be responsible for daily tasks involving the growth and differentiation of pluripotent stem cells and characterization of the target cell type.
GC Therapeutics GC Therapeutics is seeking a talented and highly motivated Scientist for our Immunology Team. The candidate will have strong expertise in immunology with extensive knowledge in the cell biology of the immune system. Reporting to the Head of Discovery Platforms, this individual will innovate on the immune aspects of novel cell therapies derived from human induced pluripotent stem cells (hiPSCs). This role will apply immunology approaches to bring a new class of cellular therapies to patients using GCTx’s Human TFome™ platform, a synthetic biology-driven technology to differentiate human stem cells. The scientist will be responsible for daily tasks involving the characterization of immune function and response for novel cell therapies.
Research Associate, Stem Cell Biology
GC Therapeutics We are seeking a talented and detail-oriented individual to join our growing stem cell research group as a research associate. Under the supervision of the Head of Discovery Platforms and senior scientists, this candidate will be responsible for the maintenance, differentiation and functional analysis of pluripotent stem cell (PSC) lines and their derivatives to support the development of cell-based therapeutics. This role will involve bringing a new class of cellular therapies to patients using GCTx’s Human TFome™ platform, a synthetic biology-driven technology to differentiate human stem cells. The candidate should be coachable, determined, well-organized, responsible, and able to collaborate with other team members.
Postdoctoral Fellow - STEM Education
Hunter College of CUNY (Research Foundation) https://www.rfcuny.org/careers/postings?pvnID=HC-2111-004396
A 1-year renewable postdoctoral research position is available as part of a major grant from the NSF-HSI Program to study the effectiveness of various practices on student persistence and retention in STEM specifically relating to the first-year experience. These include gateway STEM course revisions, faculty pedagogical development, course-based research experiences, STEM-focused learning communities, STEM-readiness activities, and STEM-focused co-curricular supports. The postdoctoral researcher will play a key role in the design, delivery, and analysis of these interventions, working as part of a large multidisciplinary team that includes faculty and staff from STEM departments, the School of Education, Student Affairs, and Learning Centers. As such, the postdoctoral researcher will participate in regular meetings with the grant team and help with overall project management. The postdoctoral researcher will work particularly closely with School of Education faculty on data collection, management, and analysis, as well as the communication of research findings via conferences and scholarly articles. The postdoctoral researcher may also coordinate and manage the research of other team members, such as graduate students.
PhD or EdD from an accredited institution in Education, Psychology, or a project-related discipline by start date of position.
Experience in both qualitative and quantitative research design, data collection, and analysis using the latest techniques and software packages in an educational field related to the project (STEM education, student retention, educational psychology, etc.)
Expertise or interest in college-level STEM education research
Ability to work independently and collaboratively as part of a large, complex, interdisciplinary team with a number of priorities
Experience in scholarly research and publication Excellent interpersonal skills
Genmab Genmab is focused on the creation and development of innovative and differentiated antibody products, with the aim of improving the lives of cancer patients.
The Role We are seeking a highly motivated (Senior) Research Scientist to join Genomics laboratory in Translational Medicine, located in Princeton, NJ. The Translational Medicine team works in concert to combine flow cytometry, immune function assays, RNA profiling, immunogenomics and spatial genomics to provide a deep phenotype of patients participating in Genmab trials. The applicant should have completed a PhD with specialization in immunology, cancer biology, bioinformatics or pathology and have significant experience with genomics. This role will require a high level of analytic experience; the goal is to integrate genomics and cytometry with clinical trial data and ultimately provide actionable insights for patient stratification, resistance mechanisms and combination strategies.
Responsibilities The primary responsibility will be to design, execute and analyze spatial genomics experiments from patient samples in oncology clinical trials and commercially sourced cohorts. The current platform used in-house is Nanostring DSP; this method generates protein and RNA abundance data for small regions defined by fluorescent antibodies in an FFPE tissue. Using this tumor microenvironment information, the candidate will apply bioinformatic techniques to identify gene/protein markers of immune infiltration, pharmacodynamic effect, response to treatment and immunosuppressive signaling. Additionally, the role will involve collaborating with antibody development teams to identify protein targets or likely combination therapeutics to drive Genmab’s pipeline. The scientist should regularly present findings to internal Genmab stakeholders and publicly at conferences or through manuscripts.
Our laboratory follows GCP guidelines, so core responsibilities will include performing assay validations, periodic quality assessm
(Senior) Scientist, Translational Sciences
Genmab Genmab is focused on the creation and development of innovative and differentiated antibody products, with the aim of improving the lives of cancer patients.
The Role Genmab is seeking a highly motivated research scientist (PhD) focused on the development of cutting-edge tumor-immune assays in our Translational Sciences group. An ideal candidate will have strong translational research experience in oncology, immune-oncology or immunology with expertise in developing and running complex primary tumor-immune assays, conducting antibody-based drug mechanism of action studies and performing analysis on multi-omics datasets to identify novel PD/biomarkers. The candidate will also work closely with our expanding Data Science team at Genmab to drive real-time probing of translational science datasets to uncover potential combination partners and provide insights and combination proof of concept for various drug programs. As a member of the Clinical Biomarker Assay Team within Translational Sciences, the candidate will work together with a team of experienced and motivated scientists to perform laboratory-based research in a collaborative team environment and interpret and present findings at project meetings to advance our portfolio and drug pipeline. Find out more here: https://genmab.wd3.myworkdayjobs.com/en-US/Genmab_Careers_Site/job/Princeton-NJ/XMLNAME--Senior--Scientist--Translational-Sciences_R2806-1
Medical Writer - Medical Communications Agency
IPG Health Medical Writers assume responsibility for understanding the scientific and clinical aspects of their assigned businesses in depth, and serve as a key resource for both internal teams and clients in medical education. They will represent the scientific perspective throughout development of manuscripts and presentations, and ensure scientific and clinical relevance. Medical Writers will begin to develop their strategic skill set in an effort to uncover the most compelling way in which to communicate brand differentiation. Demonstration of excellent written and verbal communication skills, and strong analytical and interpretive skills, is needed.
- Develop adequate scientific knowledge base for assigned products and assist with scientific platform development. - Develop manuscripts that meet the stated objectives of the project, are within the job specifications as defined by team/client, and are at the appropriate level and tone for the audience. - Address all inquiries and incorporate all revisions requested by internal, client, and KOL reviewers. - Understand marketing and strategy and objectives for assigned products. - Determine adequacy of references provided for projects and obtain additional references or information as necessary. - Provide competitive intelligence at congresses. - Able to represent medical and deliver review of content to clients. - Participate in speaker training and advisory activities. - Help identify and vet KOLs. - Participate in brand plan development for medical education accounts. - Demonstrate excellent written and verbal communication skills. - Describe the data/references used, and answer any questions regarding the piece. - Manage workflow for assigned products and ensure team deadlines. - Help define job specifications, and help generate project proposal. - Contribute innovative ways to deliver medical education content.
IPG Health Medical Associate is an entry level industry position to support Medical Directors/Department. Medical Directors assume responsibility for understanding the scientific and clinical aspects of their assigned businesses in depth and serve as a key strategic resource for both internal teams and clients. They will leverage science in brand differentiation and communications, collaborate with copywriters/medical writers to represent the scientific perspective throughout strategic/creative development, and ensure scientific and clinical relevance. At all levels, the Medical Directors will continue to develop their strategic skill set in an effort to uncover the most compelling way in which to differentiate a brand or franchise from a medically viable, but compelling perspective. Demonstration of excellent written and verbal communication skills, and strong analytical and interpretive skills, is needed.
• Take the lead on literature searches and research needs of team. • Begin to demonstrate depth of understanding for an assigned product and disease state. • Assist in development of content for assigned projects in accordance with approved outline and/or client guidelines. • Determine adequacy of references provided for projects and obtain additional references or information as necessary. • Attend client conferences and provide onsite meeting support, if needed. • Assist with research and development of background materials for new business pitches. • Be able to communicate clearly the objectives of each piece on which you work. • Describe the data/references used, and answer any questions regarding the piece. • Demonstrate willingness to assist with all team deliverables. • Participate on product team activities.
Masters of Science or PhD required.
Scientist - Chemistry
Bristol Myers Squibb Position Description • Individual will be responsible for the design and synthesis of new agents for the potential treatment of human diseases with emphasis in Cardiovascular, Fibrosis, Immunology, and Oncology disease areas. • The individual will apply modern techniques in organic chemistry and utilize current medicinal chemistry practices to solve problems of relevance to the assigned project and therapeutic area.
Position Requirements • Candidates must have a Ph.D. in organic chemistry with 0-3 years of additional related research experience. • Candidates must have experience in designing and executing multistep synthesis of complex organic molecules using modern techniques in organic chemistry. • Candidates will have expertise in the purification and characterization of organic compounds (Chromatography and NMR, MS, IR spectroscopy). • Excellent problem-solving skills and a thorough understanding of synthetic methods and reaction mechanisms are required. • Good oral/written communication skills and a desire to work in a collaborative team environment are required.
Scientist - Chemistry
Bristol Myers Squibb Position Description
Individual will be responsible for the design and synthesis of new agents for the potential treatment of human diseases with emphasis in Cardiovascular, Fibrosis, Immunology, and Oncology disease areas. The individual will apply modern techniques in organic chemistry and utilize current medicinal chemistry practices to solve problems of relevance to the assigned project and therapeutic area. Position Requirements
Candidates must have a Ph.D. in organic chemistry with 0-3 years of additional related research experience. Candidates must have experience in designing and executing multistep synthesis of complex organic molecules using modern techniques in organic chemistry. Candidates will have expertise in the purification and characterization of organic compounds (Chromatography and NMR, MS, IR spectroscopy). Excellent problem-solving skills and a thorough understanding of synthetic methods and reaction mechanisms are required. Good oral/written communication skills and a desire to work in a collaborative team environment are required.
Post-doctoral Fellow, Functional Genomics of Autoimmune Diseases
Bristol Myers Squibb Position Summary
We are seeking a Postdoctoral Fellow with training in molecular and computational biology to utilize functional genomics approaches to leverage understanding of long noncoding RNA in Inflammatory Bowel Disease and other Autoimmune Diseases. The goal of these studies will be to identify biomarkers to understand disease biology, novel target identification, indication selection, patient stratification, and target modulation. In this unique opportunity, you will be co-mentored by a translational Immunologist and Statistical Geneticist while based at BMS.
Utilize functional genomics approaches to identify and interrogate novel targets and biomarkers of autoimmune disease. Facilitate the development of internal functional genomics capabilities. Develop and implement computational approaches to integrate multiple data sources to prioritize novel disease-related targets, pathways and biomarkers. Utilize immunology, biochemistry, molecular biology, and human genetics to identify and interrogate disease-related lncRNA targets, pathways and biomarkers. Operate in a matrixed environment with internal and external partners in Immunology Early Development and Predictive Sciences teams. Represent the company to the academic community in the form of publications and/or meeting presentations. Qualifications & Experience
PhD in immunology, molecular biology, computational biology, genetics, or related discipline. Proven wet-lab and computational experience in the form of scientific productivity reflected by publication(s). Adept with molecular biology techniques, RNA expertise is essential. Working experience R and/or Python and in Unix/Linux environment is required. Working knowledge of statistical genetics is preferred, but not required. Experience analyzing NGS data (DNA-Seq, RNA-Seq, single cell) or Mass Spectrometry data is required. Demonstration of oral, written, and interpersonal skills.
Post-doctoral Fellow, Informatics and Predictive Sciences
Bristol Myers Squibb This position is for a 3-year postdoctoral fellowship as part of a world-class research team, centered upon the utilizing novel CRISPR technologies to identify disease biology and drug targets, at single cell resolution. The successful applicant will focus on developing novel technologies to assess the effects of genetic perturbation in cancer models through the modulation of gene expression. The position offers unique exposure to cutting-edge research in a biopharmaceutical industry setting, with mentorship from experienced wet-lab and computational biologists.
Develop novel CRISPR-based single cell genomic technology platforms Adapt and enhance existing analysis frameworks for single cell RNA-seq studies Work as part of a team on novel assay and protocol development Forge impactful collaborations with members of diverse disease research teams at BMS Qualifications & Experience
PhD degree in Biological Sciences or related field Strong publication record in genomics research Track record of hands-on experience developing genomics technologies to gain novel insights Strong understanding of Next Generation Sequencing platforms Demonstrated knowledge and ability to understand and analyze complex genomic datasets Expertise in algorithmic implementation and data manipulation using Python or R
Post-doctoral Fellow, Cardiovascular and Fibrotic Diseases
Bristol Myers Squibb We seek a talented and collaborative scientist to use human genetics to gain insights in disease pathobiology and enable the development of novel drugs for Heart Failure. The successful candidate will develop and apply computational pipelines to elucidate causal mechanisms through integrative analyses (e.g. Mendelian randomization) of proteomics and clinical data from public and proprietary sources to identify causal mechanisms that drive Heart Failure. The position offers an exciting opportunity to gain industry experience and interact with the broader scientific community. The candidate will work closely with collaborators at the University of Pennsylvania and other academic institutions, who are scientific leaders in the field of HF translational research. The candidate will have the opportunity to publish their work, and to present at external meetings and conferences.
Mapping protein quantitative trait loci (pQTL) across multiple contexts and data sources, including; a cohort of Heart Failure patients and UK Biobank. Test and apply statistical genetics tools to identify context-specific pQTL related to Heart Failure Perform Mendelian randomization across pQTL and multiple Cardiovascular disease endpoints Apply polygenic risk scores to segment Heart Failure patient populations based on disease mechanism Communicate findings in multiple settings (including 1:1, seminars, group, and project meetings) Qualifications & Experience
PhD in genetics/genomics, computational biology/bioinformatics, statistics, computer science/math/engineering or related field Expertise in statistical genetics, especially experience with methods such as; GWAS, eQTL/pQTL, co-localization, fine-mapping, Mendelian randomization, Polygenic risk scores or PheWAS Experience with relevant programming/scripting tools (e.g. R, MATLAB, Python, C/C++). Knowledge and/or interests in Cardiovascular disease biology a bonus. Excellent written and oral communication skills.
Post-doctoral Fellow, Immunology and Computational Biology
Bristol Myers Squibb Join the Discovery Biology Immunology team and computational biology team located in Lawrenceville, NJ. The postdoc will perform experimental and computational/ informatics analysis to identify novel genes, pathways, and transcription factor networks controlling the function and plasticity of myeloid cells subsets. They will furthermore work with large patient datasets to understand the relevance of the cellular subsets generated in vitro in comparison to the cellular subsets detected in patients. The position is a hands-on, laboratory-based role. The candidate is expected to be able to plan, design, develop methodologies and execute projects according to plans and protocols with appropriate supervision. Broad expertise in cellular biology is required with preference given to candidates with demonstrated experience in primary human cells culture systems.
Key Responsibilities Establish protocols and characterization of in vitro generated human macrophages and dendritic cells subsets using flow cytometry, functional assays and coculture systems Design experiments and analyze preclinical and clinical-omics data sets, including RNA-seq and genome wide chromatin accessibility Gene editing using CRISPR Integrative analysis of transcriptome and regulome datasets through the application of existing tools and development of custom analysis code and pipelines Qualifications & Experience Recent PhD graduate in immunology, biology, biochemistry or biological science with training in Bioinformatics or computational Biology or PhD graduate in Bioinformatics or computational biology with prior experience working in immunology lab Experience in primary human immune cell isolation, propagation and immune cell-based functional assays is required (e.g. T cells, B cells, myeloid cells, co-culture assays and other primary cell assays) Experience in flow cytometric analysis, measurement of cell surface receptors and p
Research Investigator, Clinical Pharmacology and Pharmacometrics, Hematology
Bristol Myers Squibb The Clinical Pharmacology and Pharmacometrics (CP&P) team at BMS is responsible for the pharmacology and pharmacometric support for all pipeline assets throughout the clinical development lifecycle. Composed of pharmacologists, pharmacometricians, and modelers, this group oversees the pharmacokinetic evaluation, pharmacometric exposure-response evaluation, quantitative systems pharmacology modeling, physiologically based pharmacokinetic modeling and model based meta-analysis of assets covering all platforms of therapies, including small molecules, traditional and complex biologics and next gen cell therapies. Position Responsibilities 1. With guidance, perform non-compartmental pharmacokinetic (PK) data analysis and reporting for regulatory submission using WinNonlin. 2. Under direction, provide protocol study design input and assist in the development of clinical study monitoring plans, site selection, and PK samples logistics. 3. Assist in the planning, implementing, interpreting and reporting of assigned Phase I to III PK and PK/PD studies. 4. Assist in the development of the statistical analysis plan. 5. Assist in the analysis and reporting population-pharmacokinetic and PK/PD data as necessary to describe pharmacokinetics in patient population. 6. With guidance, provide scientific oversight of CROs with respect to PK and PK/PD tasks. 7. Under direction, evaluate the relationship between exposure and pharmacodynamic (PD) properties for compounds from discovery to proof of activity to late stage Phase 3 drug development. 8. Under direction, provide PK and PK/PD strategies to compounds under drug development.
Requirements Advanced degree (Pharm.D. or Ph.D.) in pharmacokinetics/pharmacology or relevant life sciences with 0 to 2-years experience conducting and analyzing pharmacokinetic and pharmacodynamic studies in humans.
Bristol Myers Squibb The scientist in this role will work in the solid tumor Immuno-Oncology Quantitative Systems Pharmacology (I-O QSP) group to further develop established disease-level QSP models and apply them to aid in target prioritization, therapeutic modality selection, chemical/biotherapeutic optimization, biomarker characterization, combination therapy assessment, and clinical trial design. QSP modeling has become an important component of clinical development which builds on mechanistic, mathematical models, based on integration of non-clinical/clinical knowledge and data to represent disease pathophysiology and multi-drug pharmacology.
Provide leadership to and collaboration with multidisciplinary project teams to develop and apply QSP models
Proficient in the development and application of QSP models to address drug-discovery and development questions
Partner with external groups to accelerate the internal Systems Pharmacology efforts in key disease areas
Provide expert support to project teams to design, execute and interpret clinical studies with supervision
With some supervision, collaborate with stakeholders to identify and interpret experiments critical for model development and refinement
Leverage existing virtual population workflows and script-based analysis packages with supervision
With some supervision, network with stakeholders in R&ED to facilitate model development and application
With some supervision, align QSP model deliverables with the clinical pharmacology and clinical development plans
Stay informed with emerging literature and science in the systems biology/pharmacology modeling and simulation sciences
Build and maintain a personal track record of publication in the area of QSP
Maintain an active relationship with colleagues in Clinical Pharmacology & Pharmacometrics at the project level as well as in the advancement of Pharmacometrics
Ph.D. in Engineering, Mathematics, Bioinformatics, Pharmacom
Bristol Myers Squibb The successful applicant will be primarily responsible for the following:
Ability to conduct and interpret preformulation studies on potential new drug candidates with the purpose to interpret physicochemical and biopharmaceutical properties relevant to drug delivery
Provide experimental/computational/predictive input to drug discovery scientists during screening of new chemical entities, and enable drug design from lead optimization to the point of candidate identification, characterization and selection
Strategically design and guide the development of formulations suitable for use in drug discovery pharmacology studies, PK studies and initial toxicology studies
Participate in and drive strategic direction of the Discovery Pharmaceutics and Analytical Sciences group to further its ability to act as a problem solving entity for discovery teams and provide seamless transfer of candidates to development
Advance the abilities of the larger preclinical optimization organization to develop expertise in scientific areas which can enable our understanding the role of physicochemical properties in overall biopharmaceutical performance with an emphasis on modeling (i.e. GastroPlus)
PhD with 0-5 years of experience in industry in Pharmaceutical / Medicinal / Physical / Analytical Chemistry, or academic equivalent, is required
An understanding of preformulation aspects for new chemical entities is necessary along with ability to guide the generation and interpretation of preformulation laboratory data as it relates to the overall discovery process
Good written and verbal communication skills are a must
Excellent interpersonal skills demonstrating effectiveness as a team player on multidisciplinary teams resourced in a flexible and global environment is required
Knowledge on use of computers and databases for data collection, compilation, analysis, and information dissemination is a must
Experience with GastroPlus is desired but not essen
Senior Manager, Biostatistics
Bristol Myers Squibb Multiple roles: ey Responsibilities
Collaborates in design of clinical study including methodology, data analysis & interpretation, and reporting of study results. Authors and/or reviews protocol synopsis, protocol, statistical analysis plans, case-report forms, clinical study reports, associated publications, and other study level specification documents under some supervision Performs and/or validates statistical analyses, advise ways to maximize clarity of data display Communicates results to cross-functional teams, provides data interpretation in study documents such as clinical study reports, and publications. Translates scientific questions into statistical terms and statistical concepts into layman terms. Compliant with BMS processes and SOPs, adherence to global and project standards within an indication or therapeutic area and responsible for quality of deliverable. Continually develops technical knowledge of statistical methodology and how it is appropriately applied in trial design and data analysis for clear, concise, high-quality results. Continually enhances knowledge of drug development process, regulatory and commercial requirement Develops & advises team members. Effectively communicates the GBDS Mission and Vision in a fashion that generates pride, excitement and commitment within GBDS. Enables a culture of inclusiveness, respect for diversity, compliance with process and allows for the questioning and challenging of others in a respectful and constructive manner. Qualifications & Experience
Fresh PhD or MS with 2+ years’ experience in statistics or biostatistics or related scientific field with clinical trials, drug development, pharmaceutical industry or healthcare experience
STEM Retention Specialist
John Jay College of Criminal Justice - CUNY POSITION OVERVIEW The Program for Research Initiatives for Science & Math (PRISM), an award-winning undergraduate mentoring program at John Jay College (JJC) of the City University of New York is looking for a STEM Retention Specialist (SRS) to help manage and implement activities designed to engage and retain undergraduate science, math, and computer science students. This position reports to the PRISM Program Director and Associate Director, who manage the program. Primary responsibilities include running our PRISM Junior Scholars program that provides students enrolled in science and math majors at John Jay and its community college partners guidance, advisement, support, and resources that will help them achieve success in college. And supervising the creation of workshops and student cohort opportunities associated with our new HSI-STEM grant. The SRS will guide the programmatic approaches of our academic support initiatives, organize workshops, field trips, lab tours, seminars, and other events at the College; he/she will serve as a liaison to our community college partner institutions engaging students at those institutions to participate in research and articulate to JJC; she/he will work with Student Academic Success Programs and other offices at John Jay to coordinate all activities into the College’s infrastructure, he/she will track the participation and completion rates of students and other evaluation metrics, and perform other tasks as needed.
Deserve About the Role: Deserve is currently releasing and developing novel credit products and services that require new data modeling, data analysis, documentation, review and presentation across groups and clients.
In this role, your initial primary responsibility will be to support the data science team with existing python, R libraries as well as redshift and postgres databases in a technical capacity. However, as you gain experience (or if you already have it) you will help us in capturing new data (investigating possible new data sources), building models, testing models, documenting models, confirming adherence to government rules and compliance as well as presenting, teaching and showing how said models, data and processes work across the company and clients. The initial communication required will be with PhD level data scientist or experts that have similar experience. Eventually though, the communication will expand to include individuals that do not possess a technical background.
Postdoctoral Fellow, Oncology/Angiogenesis R&D
Regeneron Pharmaceuticals We are seeking an individual to join the Oncology research group at Regeneron to pursue creative biomedical research in a well-resourced and fast-paced industry environment. This candidate will conduct research on signaling pathways that modulate the tumor immune microenvironment, with a focus on the signaling crosstalk between tumor cells and immune cells. This position is for early career scientist trainees to receive a rigorous scientific training at Regeneron under the auspices of a scientist mentor for up to four years. Fellows will be expected to conduct creative exploratory research that results in publications.
In this role, a typical day might include: Lead an independent research project to investigate mechanisms by which tumor cell signaling regulates anti-tumor immunity.
Perform independent research in a highly collaborative environment, with access to state-of-the-art technologies and resources, including CRISPR, single cell RNA sequencing, bioinformatics support and FACS core.
Participate in postdoctoral program meetings. Provide research progress reports to supervisor and the program committee.
Build a strong dataset that leads to high impact peer-reviewed publications and presentations at scientific conferences.
This role might be for you if: You recently completed a PhD degree in the field of cancer biology, immunology, signal transduction or a relevant subject area.
You have proven training and technical expertise in cell biology, signal transduction and/or immunology techniques.
You possess prior knowledge or strong interest in CRISPR gene editing, scRNA-Seq, or mouse tumor models. A motivation to harness new/emerging technologies will be strongly preferred.
You have excellent communication and organizational skills and the ability to work in a highly interactive environment.
The ideal candidate for this role has a strong work ethic, independent critical thinking skills, a steadfast commitment to discovery research and a documented abilit
Postdoctoral Fellow, R&D
Regeneron Pharmaceuticals At Regeneron, we are known for our scientific excellence, our biomedical innovations, and our commitment to publishing important basic science findings – often leading the way in discovering and communicating important mechanistic insights. We are a leading science-based biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. We have a long-standing postdoctoral fellow program and are committed to training the next generation of leading scientists.
The postdoctoral fellow position is for early career scientist trainees who have finished graduate school, and received their PhDs (or MDs, DVMs, etc), to receive a rigorous scientific postdoctoral training at Regeneron under the auspices of a scientist mentor. The program spans up to four years. Fellows will be expected to conduct creative mechanistic exploratory research that results in publication. The program is academic in nature - the goal is to ask fundamental questions - not to work on Regeneron therapeutic agents.
The program consists of:
Up to four years of formal postdoctoral training in a program co-Directed by award-winning and published Regeneron scientists, committed to training postdoctoral fellows
Exposure to the biotechnology industry's most successful and innovative scientists
Opportunities to pursue ground breaking, creative biomedical research in a prestigious, well- resourced, and dynamic industry environment
Weekly postdoctoral scientist meetings to cultivate scientific rigor, creative thinking, critical reasoning, and career advancement
Support of scholarly productivity such as publications and conference presentations
As part of your Postdoctoral Training Program, you will:
Conduct forward-looking and innovative research to address a novel scientific question of your choice with the guidance of a mentor
Publish and disseminate data via external conferences and peer-reviewed publications
Regeneron Pharmaceuticals We are seeking an individual to join the Pre-Therapeutic Target Discovery (PTTD) group at Regeneron, to investigate the genetic and molecular mechanisms that 1) transcriptionally control of genes specific to vascular endothelial cells, 2) confer endothelial-cell identity and diversity (e.g. arterial, venous, organotypic), and 3) underlie vascular disease when dysregulated. Within this research, emphasis will be placed on strategies that genetically profile and target endothelial cell subtypes in vivo. These approaches include the generation of transgenic reporter and TRAP-seq alleles, next generation sequencing of RNA and translating RNA, and CRISPR-Cas9-mediated genome editing.
In this role, a typical day might include the following:
Develop and validate in cell-based systems for evaluating transcriptional regulatory elements that govern endothelial-specific gene expression
Engineer and validate transgenic and allele-targeted mouse lines for the in vivo characterization of genomic sequences required for endothelial-specificity
Generate TRAP-seq alleles for the study translating mRNAs in subtypes of endothelial cell populations (e.g. cardiac, arterial, capillary, tumor)
This job might be for you if: You possess knowledge of methods for the study of mouse embryonic development – microdissection, whole-mount imaging techniques, immunohistochemical and in situ mRNA detection methods in whole-mount and histological preparations
You have knowledge and analytical interpretation of RNA-seq, ChIP-seq, scRNA-seq
You have a background in bioinformatics; familiarity with command-line interface is a plus
The postdoctoral fellow position is for early career investigators to receive a rigorous scientific training at Regeneron under the auspices of a scientist mentor for up to four years. Fellows will be expected to conduct creative exploratory resea
Intellectual Property Officer
Michigan State University Administrative/Business/Professional, Agriculture, Research/Scientific, Administrative Professionals- AP, Full Time
Life Science Analyst / Consultant Positions Available
Acsel Health - Life Science Consulting Acsel Health is a life consulting firm that partners with renowned life science companies to guide life-changing innovations through their critical stages, from early development through market maturity. This is where your passion, perseverance, and past experience will converge in unique perspective that ignites your teams and inspires your clients. If you are a sharp thinker, fast learner, and great storyteller, come build your career with us. We are hiring experienced talent at all levels. Primary Responsibilities -Conduct advanced secondary research and primary research proficiently -Analyze data and identify relevant insights -Provide substantiated input to development of strategic recommendations -Acquire industry knowledge and establish key experience -Actively manage projects and maintain close communication with the team and clients
Application: Immediate paid internships and full-time opportunities available. Recruiting for the New York office, and remote work opportunities available within the US.
Please submit your cover letter and resume to firstname.lastname@example.org, and mention your participation in WCUB 2021.
JHUAPL We are seeking a Computational Biologist to support operational genomics research. As part of the Research & Exploratory Development Department at JHUAPL, our group conducts basic and applied research to characterize pathogen evolution and understand complex biological communities. We work to develop advanced genome sequencing and analytical approaches to support rapid data sharing, decision making, and understand variability in natural populations over time. In this role, you will conduct computational biology for environmental surveillance applications, targeting diverse biologicals ranging from viruses to marine species. You will work with a team of biologists to build systems that integrate genomic surveillance capabilities to increase the speed and utility of genomics. You will apply traditional and state-of-the-art approaches to characterize complex microbial and eukaryotic communities and develop new methods to enable future capabilities.
As a Computational Biologist you will: 1. Conduct basic and applied research and development to analyze genomics data to characterize the genetic diversity of viruses, bacteria, and eukaryotic organisms. 2. Establish and maintain collaborative research with national and international laboratories to facilitate sustainable genomics research programs. 3. Support new concept development activities to expand the utility of operational genomics research across the APL enterprise. 4. Develop and maintain effective working relationships across the Department, Laboratory, and with external sponsors.
For more details on job requirements, follow the link. If you have any questions, please feel free to reach out!
Research Program Coordinator, Herbert Irving Comprehensive Cancer Center, Columbia University
Columbia University Position Summary:
Reporting to the HICCC Associate Director for Administration, the Research Program Coordinator works with HICCC to support collaborative grants, contracts, pilot programs, and educational initiatives.
PRINCIPAL RESPONSIBILITIES Works with leadership to support complex and growing portfolio of cancer research grants through government, foundation/private and industry partners. This includes supporting the processes for development, proposal solicitation and review, and post-award progress oversight.
Supports the Cancer Center internal pilot award program including coordinating release of Request for Proposals, accepting applications, managing the review and selection process, and post-award progress reporting. Works with pilot program applicants and awardees to address questions, confirm eligibility and adherence to the funding partner requirements, as well as other issues or concerns.
Supports Cancer Center Pre-Award Process. Assists Principal Investigators and faculty in the development, review, and renewal of grants, contracts and subcontract proposals. Coordinates and facilitates pre-award grant preparation and submission process in collaboration with the Office of Research Pre-Award Core. Interfaces with Sponsored Program Administration, Columbia Technology
Position Qualifications: PhD (or Master) in a biomedical scientific discipline and a minimum of 2 years of experience in research grant writing and project management, or a combination of training, education, and experience. Experience with Research Administration is desired. Experience using Microsoft Office 365 is desired. Ability to work under pressure with multiple and competing deadlines required. Must be highly organized, with excellent communication and follow up skills. Ability to work as part of a team, with administrative, research, and financial staff. Experience with management of pre-award procedures and process for grant submission preferred.
Presidential Postdoctoral Fellows Program
Rutgers University Rutgers University welcomes applications for its inaugural cohort of the Presidential Postdoctoral Fellows Program. All applications are due by January 7, 2022, at 11:59 p.m. Appointment is for a two-year term starting July 1, 2022, with the possibility of subsequent appointment to a tenure-track faculty position at one of four Rutgers locations. Fellows will receive a $65,000 annual salary, $10,000 in discretionary research funds per year, typically teaching one class or equivalent during the academic year.
Fellows will be appointed into one of three priority areas: Race, Racism, Inequality; Health Equity; and Advancing STEM Diversity.
Research Associate - Healthcare Advertising Agency
IPG Health Our Research Associates are team members who are new to healthcare advertising and eager to learn how science and clinical data can be leveraged in brand differentiation and communications. They will work with Medical Directors to support the understanding of all the scientific aspects of their assigned accounts and new business development. Demonstration of excellent written and verbal communication skills, and strong analytical and interpretive skills, is needed.
JOB DUTIES & RESPONSIBILITIES Knowledge/Expertise • Develop a depth of understanding for assigned products, related medical areas, and competitors on an ongoing basis. • Work with medical directors to ensure that projects are technically accurate, audience appropriate, and meet stated objectives. • Research and develop outlines and select references appropriate for a project. • Identify relevant congresses and outline and prioritize abstracts.
Strategic Skills/Tools • Work with medical directors to begin to monitor and identify relevant literature and provide a point of view to internal teams and clients as needed. • Learn to review content for accuracy and in time, if it is in line with product strategy.
Relationships • Onboard new team members new to brand team, as needed.
Communication/Selling Skills • Help to develop communication platform or scientific platforms that will serve as an internal content roadmap and foundation for communications. • Help develop stimuli for market research • Attend internal and client meetings under supervision to learn skills from supervisor. Management/ Leadership • Help guide copywriters when developing high science content, determine adequacy of references, participate in team meetings; deliver work that is detailed, accurate and consistently on target.
A MD, PharmD, PhD, degree in a relevant scientific discipline is required.
Medical and Scientific Associate
Healthcare Consultancy Group Our medical and scientific teams, comprised of accomplished PhDs and MDs, translate complex science into impactful and meaningful communications for our clients. We are seeking scientists interested in a career in Medical Communications to join HCG as a Medical & Scientific Associate.
WHAT DOES A MEDICAL & SCIENTIFIC ASSOCIATE DO? Principal responsibilities include scientific content development based on relevant literature analysis, fact-checking, and participation in internal and external meetings in support of our pharmaceutical, biotech, and medical device clients. In this role, you will perform literature searches and evaluation to support development of various types of innovative deliverables, including their formatting, referencing, and annotation. In each project, you will have the opportunity to monitor and manage budget and timelines, while preserving high quality and accuracy standards. As the key member of the scientific team, you will engage and collaborate with clients and contribute to the overall team success.
QUALIFICATIONS • MD or PhD in biomedical sciences • Experience with critical evaluation of scientific/medical publications • Experience developing slide decks and manuscripts based on available evidence • PowerPoint, Word, Excel, Microsoft Outlook, and Internet research proficiency • Exceptional written and oral communication skills • Strong attention to detail and organizational skills • Demonstrated ability to perform effectively in a collaborative team structure and thrive in a fast-paced environment.
BENEFITS WE OFFER: • Competitive compensation package • Paid annual time off and holidays • Comprehensive medical, dental, vision and life insurance plans • Competitive 401(k) investment and employee stock purchase plans • Tuition reimbursement • A rewarding workplace and fun team environment
Senior Grant Program Manager
RF-CUNY/John Jay College General Description The Program for Research Initiatives for Science & Math (PRISM), an award-winning STEM retention and mentoring program at John Jay College (JJC) of the City University of New York is looking for a Senior Grant Program Manager to oversee programmatic activities, budgets, and reporting for multiple federal, state, and private grants. The Senior Manager will work directly with the PI and Dean of Research to assure that all project tasks are on schedule, supervise staff working on grant activities, balance and allocate grant budgets, and prepare annual and final reports to funding agencies. The Senior Manager will also collaborate with the PI and other project staff to design and implement effective program interventions, and craft new funding proposals to grant agencies.
As a senior team member, the Senior Manager will exercise independent judgment in implementing plans to achieve the goals and objectives of the funded projects. The position requires the management and coordination of multiple grant projects including balancing year-to year project budgets, gathering data on outcomes from multiple sources, writing reports, hiring and supervising employees, drafting of contracts, and other responsibilities. These projects broadly support major educational initiatives in the STEM disciplines at the College including: the Program for Research Initiatives in Science and Math – an award-wining program that supports underrepresented students in undergraduate research training; Visionlearning – a nationally recognized online science learning environment that provides freely available teaching material to teachers and students; Research in Action – an Open Online Courses (MOOC) that teaches critical thinking skills; and other focused efforts at the College to improve STEM-learning.
Research Associate in Behavioral Neuroscience
Maplight Therapeutics MapLight Therapeutics is a start-up company founded by Stanford professors that focuses on drug discovery for central nervous system disorders. We combine cutting-edge technologies including optogenetics and single-cell transcriptomics to identify novel drug targets and develop effective therapies to address psychiatric symptoms. We are seeking highly motivated research associates with expertise in behavioral neuroscience who will become key contributors to our discovery team. The position requires rodent handling, dosing, behavioral characterization and stereotaxic surgery as well as excellent communication and organizational skills in order to effectively drive a significant and complex workload. This is a fantastic opportunity to join a small team and translate knowledge about brain circuitry into transformative therapies.
Responsibilities Specific responsibilities include, but are not limited to: • Behavioral characterization in mouse relevant to CNS indications • Working familiarity with automated video tracking systems • Drug administration (rodent IP, SC, PO) • Stereotaxic surgery for virus injection/cannula implantation • Immunohistochemistry and confocal imaging • Data analysis and interpretation
Requirements • RA with Bachelor's degree from an accredited university in a discipline related to neuroscience with significant industry and/or academic lab experience • Ability to design and carry out experiments with limited supervision • Experience with rodent behavior is necessary • Experience with optogenetics and/or small animal surgeries is highly desired • Organized and detailed-oriented with ability to communicate results effectively • Must work cooperatively in a goal-oriented team environment • Strong communication (oral and written) skills that enable the individual to interact with all levels of management, technical and scientific personnel • Passion to contribute to the success of a cutting-edge company
Molecular Biology Research Associate
Maplight Therapeutics MapLight Therapeutics focuses on drug discovery for central nervous system disorders. Our platform utilizes cutting-edge technologies including optogenetics and spatial transcriptomics to execute a circuit-based approach to target discovery. We are seeking highly motivated research associates with expertise in molecular biology who will become key contributors to our discovery team. The position requires working within a team to leverage the MapLight platform for target discovery and target validation experiments. The ideal candidate will have a solid foundation in molecular, cellular, or biochemical techniques and the desire to apply that foundation to learning new technologies. This is a fantastic opportunity to join a small team and translate knowledge about brain circuitry into transformative therapies.
Responsibilities Specific responsibilities include, but are not limited to: • RNA/DNA isolation, qRT-PCR, Western blotting • Spatial transcriptomics • Brain tissue sectioning, immunohistochemistry, and confocal microscopy • Troubleshooting molecular and cellular assays • Maintain updated experimental protocols and SOPs • Establish relationships with outside vendors and CROs • Communicate and present experimental results within the discovery team and company-wide meetings
Requirements • BS or MS related to neurobiology with 2–5 years of experience in academic or biotechnology/pharmaceutical laboratory • Ability to design and carry out multi-step experiments with limited supervision • Experience with broad biochemical, molecular and cellular techniques • Experience with fluorescent in situ hybridization for the detection of DNA or RNA • NGS analysis and R/Python programming a plus • Organized and detail-oriented with ability to communicate results effectively • Must work cooperatively in a goal-oriented team environment • Passion to contribute to the success of a cutting-edge company
Columbia University The Zuckerman Institute seeks a talented and creative individual who possesses a passion for event production as it relates to programmatic, scientific, development and internal events in support of the overall goals of the institute. This role offers the opportunity to learn and develop event production, science communication and public engagement skills through experience.
Reporting to the Senior Director of Administrative Services, the Production Specialist will work across interdisciplinary programs to produce crossover programs that combine science, technology, engineering and mathematics (STEM) with the arts, development and other fields. The role will primarily involve designing programs, engaging with scientists, coaching scientists to communicate with general audiences, creative production and working across teams (Development, Public Programs, Scientific Programs and Human Resources) to create engaging programs. A key aspect of this work is the ability to partner and collaborate with internal departments, offices across Columbia and organizations outside of the University to create mutually beneficial programming.