Jobs Posted on the Whova Community Board of ZDM14 Virtual Conference
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Postdoc/research scientist positions - genetics in an infectious disease lab
A*STAR A*STAR Infectious Diseases Labs (A*STAR ID Labs) is seeking a postdoctoral researcher with experience in model organism genetic engineering to join us in our mission to be a leading centre of infectious diseases research. A*STAR ID Labs aims to develop a cohesive A*STAR response integrated with the National PREPARE programme, to drive and deliver translational infectious diseases research to better health and economic outcomes.
This position will be under the supervision of Dr Stefan Oehlers to utilize cutting edge live imaging and genetic techniques to analyse zebrafish infection models. A prerequisite of the position is experience with genetic engineering of a model organism including, but not limited to: zebrafish, flies, worms, mice. Specific experience with BAC transgenesis, Gateway vector engineering, and/or targeted gene deletion are desirable.
A strong desire to learn and pioneer new techniques, and an interest in host-pathogen interactions are essential.
Looking for Postdoc to study aging and cancer in zebrafish
IRCAN - Institute for Research on Cancer and Aging of Nice We focus on two main projects that attempt to answer the following questions: 1- How does telomere shortening contribute to ageing? and 2- Why does cancer incidence increase with age (and if telomere shortening is responsible)? To answer these questions, we use zebrafish that shortens telomeres as they age, just as humans do. Our laboratory has recently relocated to the IRCAN (www.ircan.org) at the beautiful city of Nice, France in the Côte d'Azur and we have plenty of opportunities to explore together. If you are interested, please send a CV, your research interests and the name of two referees to Miguel-Godinho.FERREIRA@unice.fr. Spread the word and get in touch!
Postdoctoral Fellowships available
Children's Hospital Los Angeles We are recruiting two postdoctoral fellows for newly-funded projects using zebrafish models to understand disease mechanisms and develop new treatments for pediatric cancers. We have a major focus on sarcomas driven by fusion oncogenes. Come join a fantastic team at a great institution!
University of Michigan We study blood and cardiovascular disorders using the zebrafish model.
NC State University The person taking this position, will utilize zebrafish embryos and human cell lines to assess the impact of exposure to environmental chemicals on innate immune function. This individual will organize and execute (1) toxicology-based experiments to evaluate computer automated in vivo imaging of zebrafish embryos to manual imaging of embryos, and (2) immunotoxicology-based experiments to evaluate the impact of PFAS exposure on zebrafish embryos and human cell lines.
Assistent academic staff - PhD fellow
University of Ghent Subject of the dissertation: Prediction of surgical resectability after FOLFIRINOX chemotherapy for borderline resectable and locally advanced pancreatic cancer
After neoadjuvant therapy, borderline resectable (BR) and locally advanced pancreatic ductal adenocarcinoma (LAPDA) patients need to be evaluated by a surgeon whether they may be eligible/will benefit from surgery. However, surgical resectability is difficult to predict as spatial changes are unreliable on CT-scans and the tumor marker (CA 19-9) is not specific enough. Patients with circulating tumor cells (CTCs) in their blood in a pre-operative setting show a detrimental outcome despite successful tumor resections. Indeed, CTC presence predicts early distant metastases and impaired survival. However, isolating CTCs from blood samples is not a routine laboratory test. In fact, characterizing such CTCs requires optimizing the isolation procedure of this rare cell population and the development of proper single-cell analyses.
Langenau Lab Manger - Boston, MA
Massachusetts General Hospital The Langenau Lab Research Manager will administratively oversee the running of the research laboratory (including management of research technicians), and manage spending and budgets of the portfolio of grants that fund work in the Langenau lab. S/he works independently with minimal supervision to ensure efficient operation of the Langenau laboratory with administrative oversight over all lab functions. Allocates, budgets, and regulates spending on the multiple grants that fund work in the lab and contributes to the assembly of progress reports to funding agencies.
Job flexibility is possible with this position. An individual wanting a full-time exempt employee position would perform 60% administrative duties outlined below and 40% molecular biology and lab experimentation. Alternatively, a flex hour part-time position could be envisioned that would be 20-24 hours weekly and minimally include one onsite day/week in the lab. Other hours could be worked remotely and meetings held with lab members via Zoom. Flexibility of daily working hours is also possible to foster a good home, work-life balance. A flex schedule will be established to meet the needs individual and lab at the time of interviewing.
The Langenau lab uses zebrafish as a discovery tool for understanding human cancer.
Contact David Langenau at Mass General Hospital, Boston for more information - email@example.com
Research Fellowship in Langenau Lab – Pediatric Cancer, Stem Cells, and Zebrafish Xenograft Modeling
Massachusetts General Hospital The Department of Molecular Pathology/Cancer Center at Massachusetts General Hospital is seeking two research fellows to work in the laboratory of Dr. David Langenau. As part of the dynamic network of researchers in both the Department of Pathology and the Cancer Center at Massachusetts General Hospital, these individuals will be integrated into both the medical and research community at Harvard Medical School.
Research will focus on using zebrafish cancer models, mouse xenografts, and human cell lines to better understand how pediatric muscle tumors and leukemia relapse following conventional chemotherapeutic intervention. Projects will center on using cutting-edge live cell imaging to visualize cancer development in fluorescent-labeled zebrafish. Work will also involve use of human cell lines, biochemistry, molecular biology, and mouse xenografts. Dr. Langenau’s research interests are best summarized in the following manuscripts (Yan et al., JEM, 2021; Yan et al., Cell, 2019; Hayes et al., Cell Stem Cell 2018; Lobbardi et al., Cancer Discovery 2017; Blackburn et al., Cancer Cell 2014; Ignatius et al., Cancer Cell 2012).
Please send a CV/resume and 2 references of contact to Dr. David Langenau (firstname.lastname@example.org). Please title your email “Fellowship Application”. Salary will be based on years of experience and will be competitive with pay scales at all Harvard Affiliated Hospitals.
David M. Langenau, PhD Associate Chief of Research Department of Pathology, Massachusetts General Hospital Professor of Pathology, Harvard Medical School 149 13th Street, office #6012 Charlestown, Massachusetts 02129
Postdoctoral Scholar in the Kendall Lab - Pediatric Cancer
Nationwide Children's Hospital / The Ohio State University *Please reach out to Dr. Kendall directly if interested (Genevieve.Kendall@NationwideChildrens.org)
This position is in the Center for Childhood Cancer and Blood Diseases in Dr. Genevieve Kendall’s lab. We are seeking a motivated postdoctoral scholar to join our lab group. Our team is focused on developing basic and translational models of pediatric sarcomas, which are devastating and aggressive solid tumors with limited therapeutic options. Specifically, we study rhabdomyosarcoma, which is thought to arise from a misregulation of skeletal muscle developmental pathways. We use cell culture and transgenic zebrafish systems to understand the underlying biology of the disease and then apply that knowledge to identify therapeutic targets. Identified targets and therapeutic strategies are then confirmed via our model systems and through collaborations with the extensive expertise present in the Center for Childhood Cancer and Blood Diseases, Division of Hematology/Oncology and BMT, and in the Institute for Genomic Medicine. With guidance from Dr. Kendall, you will be responsible for leading an independent project that addresses our shared interests and aligns with your career goals. Your responsibilities will include performing experiments, determining the next steps, developing and implementing new and existing protocols, analyzing and presenting your results and conclusions, generating figures, and writing and publishing manuscripts. A background in zebrafish modeling of disease, skeletal muscle development, RNAseq, ATACseq and single cell sequencing is not required, but would be beneficial. The selected candidate must be professional, self-motivated, and dedicated, with strong communication and interpersonal skill sets that will fit our team. You will have many opportunities to learn new skill sets, present your work, develop professionally, and contribute to identifying new therapies for pediatric cancers in a dynamic and positive environment.
Post Doc position
University of Colorado Anschutz Medical Campus open post doc positions! check it out here https://medschool.cuanschutz.edu/pediatrics/sections/developmental-biology/training/postdoctoral-training
University of Alabama at Birmingham Medical School The Thyme lab (https://www.thymelab.org/) uses zebrafish as a model system to understand the genetic mechanisms underlying psychiatric and neurodevelopmental disease. We also employ protein engineering techniques to build tools to assist with our zebrafish studies. Experiments will potentially utilize the following techniques, depending on the project: molecular biology (PCR, cloning), zebrafish genome-editing, zebrafish line maintenance, antibody staining, RNA in situ analysis, high-resolution imaging, biochemistry (protein purification), bacterial directed evolution, high-throughput larval behavior, drug screens, and transcriptomics (bulk and single-cell RNA-seq). Analysis of most data from the lab requires cluster computing, and postdocs will be trained in this area as well as in python scripting or other languages if there is an interest or need.
The lab opened in July 2019 and Dr. Thyme has already been awarded several highly prestigious new faculty awards, including the Klingenstein-Simons Fellowship and the limited submission Mallinckrodt Grant. Current research includes genes that increase risk for autism and schizophrenia, unstudied proteins with domains of unknown function (the dark proteome) and likely neurobiological roles, and conserved alternative splicing events that are important to normal neurodevelopment.
The lab location at UAB offers fantastic weather and a very reasonable cost of living, facilitating a positive postdoc experience. UAB is a world-class institution, ranked the number one young University in the US for multiple years in a row and in the top 10 among public universities for NIH funding.
UAB also offers an IRACDA postdoctoral fellowship for those with a strong interest in training for teaching positions (applications typically due in February). The Thyme lab would consider applicants arriving at later dates, particularly those interested in applying to the IRACDA program, or in the immediate future.
University of Mississippi medical Center Tooth development and evolution in zebrafish
University of Mississippi medical Center Post doctoral position in the Gibert lab to study diabetes and obesity in zebrafish
Postdoc Position(s) Mosimann and Burger Labs
University of Colorado School of Medicine, Anschutz Medical Campus To expand our lab’s international team at the University of Colorado School of Medicine, Section of Developmental Biology, we are looking to recruit a postdoctoral fellow (within 2 years of graduating from their doctoral degree).
Our lab’s research aims to elucidate the molecular mechanisms of cell fate determination during the formation of universal features of the vertebrate body plan. As main paradigm, we study the developmental emergence and patterning of the lateral plate mesoderm (LPM), the elusive joint origin of the cardiovascular, blood, kidney, and limb lineages.
We study the LPM and its molecular regulation using advanced transgenic approaches, gene-regulatory element discovery, genome editing, cross-species comparisons, and lightsheet imaging using the zebrafish as principal model. Our work provides an interface to developmental biology, evo-devo, and disease modeling projects that we also pursue with an international network of collaborators. A special interest are the genetic causes of congenital cardiac, endothelial, and hematopoietic disease. More info about our lab and our current lab members can be found on our lab website: www.mosimannlab.org.
We offer an international, interactive, inclusive, and collaborative lab environment with access to state-of-the-art imaging resources and facilities. Our lab is located at the Anschutz Medical Campus within the Department of Pediatrics, Section of Developmental Biology, embedded in a growing framework of basic and clinically oriented research labs.
Interested? Please get in touch with Christian Mosimann (christian.mosimann at cuanschutz.edu ) or Alexa Burger (alexa.burger at cuanschutz.edu ) for more info on the application process – we’d love to hear from you. Come join us in beautiful Colorado!
Tenure-track Assistant Professor in Neurobiology/Neuroscience
UNC Chapel Hill We seek outstanding candidates in any field of basic neuroscience, including (but not limited to) systems, cellular, and behavioral neuroscience. We are especially interested in researchers utilizing experimental model organisms, such as Drosophila, C. elegans, and zebrafish, although those using other experimental organisms or studying neurological disease models are encouraged to apply. The ideal candidate may employ a combination of approaches, including, but not limited to: advanced cellular or molecular imaging, electrophysiology, quantitative analysis of behavior, genetic manipulation of neural circuits or molecules, biochemistry, and computational modeling.
Sanford Burnham Prebys Medical Discovery Institute Augmented Regeneration: Enhancing Endogenous Mechanisms and Inducing In Vivo Transdifferentiation
Our lab is interested in basic and applied biology, in the fields of development, regeneration, and aging. Current research projects are primarily focused on understanding and stimulating regeneration by leveraging three recent breakthroughs from our laboratory. First, we have identified a novel regenerative stem cell source that we are coaxing to enhance organ repair for liver and pancreatic diseases, such as Alagille Syndrome (publication ) and diabetes. Second, we have identified a first-in-class small molecule, directly targeting a key signaling pathway implicated in regulating somatic stem cells, that can enhance liver regeneration (video ). We are now developing this patent pending drug as a basic science research tool and as a potential therapeutic for disorders affecting several other organs systems. And third, we have developed an effective and efficient new vertebrate platform for investigating induced in vivo transdifferentiation as a strategy for generating replacement cells directly in the body, independent of transplantation and iPSC approaches, and discovered that functionally differentiated muscle cells are still amenable to be converted into completely unrelated cell types of a different germ layer (preprint ). Extending on this breakthrough, we recently identified two novel mechanisms which are required for in vivo transdifferentiation and can be leveraged to enhance this cell identity conversion process.
Our lab, located in coastal, sunny San Diego (a mecca of academia, biotech, and pharma), offers exciting projects, rigorous training, mentoring, a friendly work environment, and a competitive salary (starting at ~$60K annual salary, with benefits).
Post-doc /Tech in imaging metastasis
INSERM, CRBS, Goetz lab The Goetz Lab at INSERM U1109 (Tumor Biomechanics, www.goetzlab.com, CRBS, Strasbourg) is seeking a talented postdoctoral/engineer scientist with background in Microscopy and Cancer biology Our lab uses advanced imaging techniques coupled to microfluidics and animal models to study tumor metastasis at multiple scales. The lab is actively investigating the contribution of mechanical forces as well as extracellular vesicles in metastasis onset. Our approach permits real-time imaging ranging from single-cell metastatic events to whole body tumor progression. Doing so, we aim at understanding how metastasis occurs in relevant and controlled animal models (Goetz et al., 2011, 2014; Follain et al., 2018; Hyenne et al., 2019; Osmani et al., 2019 Ghoroghi et al., 2021). Our lab has developed, in collaboration with the EMBL and the DKFZ (Heidelberg) unique imaging technologies that offer nanoscale mapping of cellular and subcellular architecture in their most representative environment, notably intravital Correlative Light and Electron Microscopy (iCLEM) (Follain et al., 2018; Hyenne et al., 2019; Karreman et al., 2014, 2016). Our lab has recently relocated into the Center for Biomedical Research of Strasbourg (CRBS), a new institute that is equipped with multiple platforms and facilities (mouse and zebrafish husbandry, imaging facility, sequencing platform). We benefit from a proximity and regular collaborations with the IGBMC (Illkirch), EFS (Strasbourg), EMBL/DKFZ (Heidelberg) for both photonic and electron microscopy. In addition, the lab is engaged in collaboration with the team of Paul Timpson (Garvan Institute, Sydney) a world-leader in intravital imaging. The successful candidate will join an interdisciplinary team made of cell and cancer biologists, molecular biologists and physicist. The candidate will study several aspects of the metastasis cascade, including tumor cell deformability, and participate in setting up intravital imaging protocols of extracellular.
NC State University The Marsden Lab is seeking a postdoctoral researcher to spearhead a project investigating the cellular and molecular mechanisms that regulate sensory responsiveness. Sensory over-responsiveness is a debilitating condition often experienced by those with anxiety disorders and/or autism, and so this work is very clinically relevant. The project will combine high-resolution imaging of synapse dynamics, neuronal activity, and behavior to uncover links between the actin cytoskeleton, neural circuit function, and auditory sensitivity.
2 Tenure-track Faculty Positions in Neurobiology
NC State University The Department of Biological Sciences in the College of Sciences at North Carolina State University seeks outstanding candidates for two tenure-track faculty positions in neurobiology at the preferred rank of Assistant Professor, although exceptional candidates for Associate Professor will be considered.
Applicants should have a doctoral degree and relevant postdoctoral experience. We are seeking candidates who employ cutting-edge and innovative approaches that build on existing strengths in our growing interdepartmental and intercollegiate neuroscience community and that can bridge with departmental expertise in genetics and environmental health. Candidates pursuing research in all areas of neurobiology are encouraged to apply, and there is particular interest in candidates with expertise in computational and systems neuroscience, glial biology, neurophysiology, and neuroethology.
Candidates studying standard or nontraditional model organisms and/or natural populations are encouraged to apply. The successful candidates will be expected to develop and/or maintain extramurally funded, nationally recognized, independent research programs and also support the academic mission of the department including undergraduate, graduate, and postdoctoral training programs. Inclusiveness and diversity are critical to the success of the Department and University as a whole; the new faculty member will be expected to actively contribute to a community that is respectful, inclusive, and welcoming of all groups.
Emory University School of Medicine The Henke lab at Emory University is looking to hire a motivated research technician to join our group to investigate gene function during development, homeostasis and disease of the musculoskeletal system using the zebrafish as a model. We utilize the CRISPR/Cas9 system to generate new genetic tools; phenotyping by microCT, histology and enzymatic stains; as well as transcriptomic profiling. Responsibilities will include collecting, organizing and reporting research data under minimal supervision; assisting in the design of experiments; maintaining laboratory supplies and equipment; instructing others in basic laboratory techniques; collecting and summarizing data; monitoring results; reporting unusual outcomes. Necessary skills include organization, critical thinking, communication skills, standard lab notebook practices; attention to detail.
Required education and experience: BS or BA in biological sciences required, experience with basic programming and working with zebrafish are a plus.
To initially apply, please send your CV and a brief description of why your are interested in joining the lab. We will send out an official application link if we feel you are a good fit.
2 postdoctoral positions
National Human Genome Research Institute 1) Position title: Bioinformatics and genome assembly
Funded postdoctoral positions are available in the laboratory of Dr. Shawn Burgess, within the Translational and Functional Genomics Branch of the National Human Genome Research Institute, at the National Institutes of Health.
The Burgess lab is looking for Postdoctoral candidate interested in participating in a variety of bioinformatics-based projects (or wet/dry hybrid projects) in collaboration with Dr. Adam Phillippy, in particular high-quality genome assembly of both model and non-model organisms, particularly the zebrafish genome.
2) Position title: Functional genomics of tissue regeneration
Funded postdoctoral positions are available in the laboratory of Dr. Shawn Burgess, within the Translational and Functional Genomics Branch of the National Human Genome Research Institute, at the National Institutes of Health.
The focus of the Burgess lab is on the genetics and functional genomics of tissue regeneration and wound healing with an emphasis on hearing regeneration in zebrafish. There are multiple projects available to pursue involving genetic analysis with high-throughput mutagenesis approaches, computational analysis of genomic data at multiple levels of genome organization, and cross-species genome assembly and analysis. Most experiments involve aquatic vertebrates, but mammalian and invertebrate projects will also be considered within the context of regeneration. Salary will be commensurate with research experience.
Qualifications: Successful candidates should have or be very close to obtaining a PhD, and have less than two years of Postdoctoral experience. To Apply: Candidates should submit their curriculum vitae, cover letter, and names and contact information for three referees to Dr. Shawn Burgess at email@example.com.
Positions are available immediately and will stay open until filled.
Research Technician - Marsden Lab
NC State University The Marsden Lab (https://marsdenlab.wordpress.ncsu.edu) is looking to hire a research technician to manage our zebrafish facility, organize and maintain the lab's supplies, train graduate and undergraduate students, and facilitate all of our projects studying the genetic and environmental factors that regulate neural development and behavior. Qualifications: Master's degree in genetics, neuroscience or related field OR a Bachelor's degree plus 3 years of relevant experience. Experience with zebrafish is a major plus, but not required. Outstanding organizational skills and excitement for science ARE required! Please contact Dr. Kurt Marsden (firstname.lastname@example.org) with any questions regarding the position.